IpiRecord: IPI00184848

IPI00184848 - ABCB11, BILE SALT EXPORT PUMP.
Uniprot Accession: Q9UIL3
Uniprot ID: Q9UIL3_HUMAN
Mapping: Chr 2, 169487694 - 169596079
Entrez Gene: 8647
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4237)
Rat: Abcb11, BILE SALT EXPORT PUMP.
Mouse: Abcb11, BILE SALT EXPORT PUMP.
Mouse: Abcb11, ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER 11.
Rat: Abcb11, SIMILAR TO BILE SALT EXPORT PUMP.
Human: ABCB11, BILE SALT EXPORT PUMP.

Annotations for ABCB11 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
apical plasma membraneCIDA 
integral to plasma membraneCTAS ISS 
membrane fractionCTAS IDA ISS 
membraneCIEA IEA IEA 
plasma membraneCIDA 
integral to membraneCRCA ISS IEA 
intercellular canaliculusCIEA IDA ISS 
Golgi apparatusCIDA 
Golgi membraneCIDA 
nucleoside-triphosphatase activityFIEA 
sodium-exporting ATPase activity, phosphorylative mechanismFTAS ISS 
ATPase activityFIEA IEA IEA 
ATPase activity, coupled to transmembrane movement of substancesFIEA IEA 
bile acid-exporting ATPase activityFTAS ISS 
transporter activityFTAS ISS 
drug transporter activityFIDA 
ATP bindingFTAS IEA IEA ISS IEA 
canalicular bile acid transmembrane transporter activityFIDA 
protein bindingFIPI IPI 
nucleotide bindingFIEA IEA IEA IEA 
catalytic activityFIEA 
drug exportPIDA 
transportPTAS IEA IEA ISS IEA 
response to oxidative stressPIEP 
metabolic processPIEA 
response to drugPIMP 
canalicular bile acid transportPIDA 
response to estrogen stimulusPIEP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
liver/biliary system phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
growth/size phenotypeMPUn
cholestasisNIED

Disease (4)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Cholestasis, IntrahepaticDISS
CholestasisDIED
Liver Neoplasms, ExperimentalDIED
EndotoxemiaDIEP

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
ABC transporters - General (02010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway