| IPI00184848 - ABCB11, BILE SALT EXPORT PUMP. | |
|---|---|
| Uniprot Accession: Q9UIL3 | |
| Uniprot ID: Q9UIL3_HUMAN | |
| Mapping: Chr 2, 169487694 - 169596079 | |
| Entrez Gene: 8647 | |
| Entrez MapView: |
|
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4237) |
|---|
| Rat: Abcb11, BILE SALT EXPORT PUMP. |
| Mouse: Abcb11, BILE SALT EXPORT PUMP. |
| Mouse: Abcb11, ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER 11. |
| Rat: Abcb11, SIMILAR TO BILE SALT EXPORT PUMP. |
| Human: ABCB11, BILE SALT EXPORT PUMP. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| apical plasma membrane | C | IDA | ||
| integral to plasma membrane | C | TAS | ISS | |
| membrane fraction | C | TAS | IDA | ISS |
| membrane | C | IEA | IEA | IEA |
| plasma membrane | C | IDA | ||
| integral to membrane | C | RCA | ISS IEA | |
| intercellular canaliculus | C | IEA | IDA | ISS |
| Golgi apparatus | C | IDA | ||
| Golgi membrane | C | IDA | ||
| nucleoside-triphosphatase activity | F | IEA | ||
| sodium-exporting ATPase activity, phosphorylative mechanism | F | TAS | ISS | |
| ATPase activity | F | IEA | IEA | IEA |
| ATPase activity, coupled to transmembrane movement of substances | F | IEA | IEA | |
| bile acid-exporting ATPase activity | F | TAS | ISS | |
| transporter activity | F | TAS | ISS | |
| drug transporter activity | F | IDA | ||
| ATP binding | F | TAS | IEA IEA | ISS IEA |
| canalicular bile acid transmembrane transporter activity | F | IDA | ||
| protein binding | F | IPI IPI | ||
| nucleotide binding | F | IEA | IEA IEA | IEA |
| catalytic activity | F | IEA | ||
| drug export | P | IDA | ||
| transport | P | TAS | IEA IEA | ISS IEA |
| response to oxidative stress | P | IEP | ||
| metabolic process | P | IEA | ||
| response to drug | P | IMP | ||
| canalicular bile acid transport | P | IDA | ||
| response to estrogen stimulus | P | IEP |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| liver/biliary system phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| growth/size phenotype | MP | Un | ||
| cholestasis | N | IED |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Cholestasis, Intrahepatic | D | ISS | ||
| Cholestasis | D | IED | ||
| Liver Neoplasms, Experimental | D | IED | ||
| Endotoxemia | D | IEP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| ABC transporters - General (02010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |