| IPI00216232 - NOS1, ISOFORM 4 OF NITRIC-OXIDE SYNTHASE, BRAIN. | |
|---|---|
| Uniprot Accession: P29475-4 | |
| Uniprot ID: NOS1_HUMAN | |
| Mapping: Chr 12, 116135362 - 116283965 | |
| Entrez Gene: 4842 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11082) |
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| Rat: Nos1, ISOFORM N-NOS-1 OF NITRIC-OXIDE SYNTHASE, BRAIN. |
| Mouse: Nos1, ISOFORM N-NOS-1 OF NITRIC-OXIDE SYNTHASE, BRAIN. |
| Mouse: Nos1, ISOFORM N-NOS-2 OF NITRIC-OXIDE SYNTHASE, BRAIN. |
| Mouse: Nos1, ISOFORM NNOS BETA OF NITRIC-OXIDE SYNTHASE, BRAIN. |
| Mouse: Nos1, ISOFORM NNOS MU OF NITRIC-OXIDE SYNTHASE, BRAIN. |
| Mouse: Nos1, ISOFORM NNOS GAMMA OF NITRIC-OXIDE SYNTHASE, BRAIN. |
| Rat: Nos1, ISOFORM N-NOS-2 OF NITRIC-OXIDE SYNTHASE, BRAIN. |
| Rat: Nos1, ISOFORM PNNOS OF NITRIC-OXIDE SYNTHASE, BRAIN. |
| Rat: Nos1, 41 KDA PROTEIN. |
| Human: NOS1, ISOFORM 4 OF NITRIC-OXIDE SYNTHASE, BRAIN. |
| Human: NOS1, ISOFORM 1 OF NITRIC-OXIDE SYNTHASE, BRAIN. |
| Human: NOS1, ISOFORM 3 OF NITRIC-OXIDE SYNTHASE, BRAIN. |
| Human: NOS1, ISOFORM 2 OF NITRIC-OXIDE SYNTHASE, BRAIN. |
| Human: NOS1, 4 KDA PROTEIN. |
| Human: NOS1, NEURONAL NITRIC-OXIDE SYNTHASE ISOFORM MU. |
| Human: NOS1, 2 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | IDA IDA | ||
| plasma membrane | C | IDA | ||
| cytosol | C | IDA | ||
| membrane | C | IEA | ||
| dendrite | C | IDA | ||
| mitochondrial outer membrane | C | IDA | ||
| cell projection | C | IEA | ||
| synapse | C | IDA | IDA ISS | |
| nuclear membrane | C | IDA | ||
| mitochondrion | C | ISS | IDA | |
| nucleus | C | IDA | ||
| membrane fraction | C | ISS | ||
| sarcolemma | C | IDA | ||
| azurophil granule | C | IDA | ||
| FAD binding | F | IEA | TAS IDA | |
| metal ion binding | F | IEA | ||
| NADP binding | F | IEA | TAS IDA | |
| FMN binding | F | IEA | TAS IDA | |
| iron ion binding | F | IEA IEA | ||
| oxidoreductase activity | F | IEA | IEA IEA | |
| electron carrier activity | F | IEA | ||
| nitric-oxide synthase activity | F | IEA | IEA IEA | TAS ISS IDA IDA |
| protein binding | F | ISS | IPI | |
| amino acid binding | F | TAS | ||
| heme binding | F | IEA | TAS | |
| enzyme binding | F | IPI | ||
| calmodulin binding | F | IEA IEA | IDA | |
| nitric oxide biosynthetic process | P | IEA | IDA | |
| striated muscle contraction | P | IMP | ISS | |
| cell-cell signaling | P | ISS | ||
| regulation of sodium ion transport | P | IMP | ||
| exogenous drug catabolic process | P | IMP | ||
| synaptic transmission | P | ISS | ||
| negative regulation of calcium ion transport | P | IMP | ||
| negative regulation of hydrolase activity | P | IMP | ||
| negative regulation of blood pressure | P | IMP | ||
| negative regulation of heart contraction | P | IMP | ||
| negative regulation of potassium ion transport | P | IMP | ||
| regulation of heart contraction | P | IMP | ||
| electron transport | P | IEA | IDA | |
| muscle contraction | P | ISS | ||
| response to ethanol | P | IEP |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| behavior/neurological phenotype | MP | Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un | ||
| nervous system phenotype | MP | Un Un Un | ||
| vision/eye phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un Un | ||
| reproductive system phenotype | MP | Un Un | ||
| growth/size phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Kidney Failure, Chronic | D | IEP | ||
| Obesity | D | IEP | ||
| Sepsis | D | IPM | ||
| Memory Disorders | D | IPM | ||
| Fetal Anoxia | D | IEP | ||
| Cardiomegaly | D | IEP | ||
| Diabetes Mellitus, Non-Insulin-Dependent | D | IEP | ||
| Nephrotic Syndrome | D | IEP | ||
| Diabetes Mellitus, Experimental | D | IEP | ||
| Myocardial Diseases | D | IEP | ||
| Arteriosclerosis | D | ISS | ||
| Hypertension, Renovascular | D | IEP | ||
| Cardiomyopathy, Alcoholic | D | IEP | ||
| Brain Ischemia | D | IPM | ||
| Diabetic Retinopathy | D | IEP | ||
| Hepatic Encephalopathy | D | IEP | ||
| Heat Stroke | D | IEP | ||
| Reperfusion Injury | D | IPM | ||
| Heart Failure, Congestive | D | IEP | ||
| Hypertension | D | IEPIEPIEPIEP |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Parkinson disease pathway | W | ISS | ||
| arginine and proline metabolic pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Long-term depression (04730) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Calcium signaling pathway (04020) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Arginine and proline metabolism (00330) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |