| IPI00217906 - GNAI2, ISOFORM 2 OF GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2 SUBUNIT. | |
|---|---|
| Uniprot Accession: P04899-2 | |
| Uniprot ID: GNAI2_HUMAN | |
| Mapping: Chr 3, 50239173 - 50271775 | |
| Entrez Gene: 2771 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_8336) |
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| Rat: Gnai2, GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2 SUBUNIT. |
| Mouse: Gnai2, GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2 SUBUNIT. |
| Mouse: Gnai2, INHIBITING 2, FULL INSERT SEQUENCE. |
| Human: GNAI2, ISOFORM 2 OF GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2 SUBUNIT. |
| Human: GNAI2, GALPHAI2 PROTEIN. |
| Human: GNAI2, ISOFORM 1 OF GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2 SUBUNIT. |
| Human: GNAI2, 20 KDA PROTEIN. |
| Human: GNAI2, 12 KDA PROTEIN. |
| Human: GNAI2, WUGSC:H_LUCA15.1 PROTEIN. |
| Human: GNAI2, 19 KDA PROTEIN. |
| Human: GNAI2, 27 KDA PROTEIN. |
| Human: GNAI2, 35 KDA PROTEIN. |
| Human: GNAI2, 9 KDA PROTEIN. |
| Human: GNAI2, 6 KDA PROTEIN. |
| Human: GNAI2, 39 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| lipid raft | C | IDA | ||
| plasma membrane | C | IDA | ||
| nucleus | C | IDA | ||
| cytosol | C | IDA | ||
| membrane fraction | C | IDA | ||
| GTPase activity | F | TAS | ISS ISS | |
| signal transducer activity | F | IEA | IEA IEA | IEA |
| GTP binding | F | IEA | ISS | IEA |
| protein binding | F | IPI | ISS IEA | |
| guanyl nucleotide binding | F | IEA | IEA | |
| nucleotide binding | F | IEA | IEA | IEA |
| response to nutrient | P | ISS | ||
| acetylcholine receptor signaling, muscarinic pathway | P | IMP | ISS IEA | |
| negative regulation of synaptic transmission | P | IDA | ||
| G-protein coupled receptor protein signaling pathway | P | IEA | TAS | ISS ISS IDA |
| cell proliferation | P | IPI | ISS IEA | |
| protein kinase cascade | P | IMP | ||
| metabotropic glutamate receptor signaling pathway | P | IDA | ||
| positive regulation of cell proliferation | P | IMP | ||
| regulation of heart contraction | P | IMP | ||
| gamma-aminobutyric acid signaling pathway | P | IDA | ||
| G-protein signaling, adenylate cyclase inhibiting pathway | P | IMP ISS IGI | ISS IEA | |
| negative regulation of calcium ion transport via voltage gated calcium channel | P | IDA | ||
| activation of MAPKK activity | P | IMP | ||
| adenosine receptor signaling pathway | P | IDA | ||
| signal transduction | P | IEA | IEA IEA | ISS IEA |
| negative regulation of adenylate cyclase activity | P | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| endocrine/exocrine gland phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un | ||
| immune system phenotype | MP | Un Un | ||
| lethality-postnatal | MP | Un | ||
| tumorigenesis | MP | Un | ||
| normal phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un Un | ||
| cardiovascular system phenotype | MP | Un | ||
| hematopoietic system phenotype | MP | Un Un | ||
| no phenotypic analysis | MP | Un | ||
| growth/size phenotype | MP | Un Un | ||
| life span-post-weaning/aging | MP | Un Un Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Tachycardia, Ventricular | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Long-term depression (04730) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Leukocyte transendothelial migration (04670) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Tight junction (04530) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Axon guidance (04360) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Gap junction (04540) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |