IpiRecord: IPI00218201

IPI00218201 - CSF1, ISOFORM 2 OF MACROPHAGE COLONY-STIMULATING FACTOR 1 PRECURSOR.
Uniprot Accession: Q5VVF3
Uniprot ID: Q5VVF3_HUMAN
Mapping: Chr 1, 110254778 - 110275144
Entrez Gene: 1435
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2530)
Rat: Csf1, MACROPHAGE COLONY-STIMULATING FACTOR 1 PRECURSOR.
Mouse: Csf1, ISOFORM 1 OF MACROPHAGE COLONY-STIMULATING FACTOR 1 PRECURSOR.
Mouse: Csf1, ISOFORM 2 OF MACROPHAGE COLONY-STIMULATING FACTOR 1 PRECURSOR.
Rat: Csf1, 58 KDA PROTEIN.
Human: CSF1, ISOFORM 1 OF MACROPHAGE COLONY-STIMULATING FACTOR 1 PRECURSOR.
Human: CSF1, ISOFORM 2 OF MACROPHAGE COLONY-STIMULATING FACTOR 1 PRECURSOR.
Human: CSF1, ISOFORM 3 OF MACROPHAGE COLONY-STIMULATING FACTOR 1 PRECURSOR.
Human: CSF1, COLONY STIMULATING FACTOR 1 ISOFORM A VARIANT (FRAGMENT).

Annotations for CSF1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCTAS 
integral to membraneCIEA IEA IEA 
membraneCIEA IEA 
extracellular spaceCIEA IEA 
cytokine activityFIEA ISS IEA 
protein bindingFIPI 
growth factor activityFIEA IEA IEA IEA 
odontogenesisPIMP 
regulation of ossificationPIMP ISS 
positive regulation of cell-matrix adhesionPIGI 
positive regulation of Ras protein signal transductionPIDA 
ossificationPIMP 
cellular processPRCA 
positive regulation of cell proliferationPISS 
positive regulation of osteoclast differentiationPIDA IGI ISS 
osteoclast differentiationPIMP TAS 
positive regulation of odontogenesis (sensu Vertebrata)PIMP ISS 
positive regulation of body sizePIMP ISS 
macrophage differentiationPIEP 
positive regulation of cell migrationPIGI 
positive regulation of protein kinase activityPIGI 
multicellular organismal developmentPTAS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (18)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
craniofacial phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
other phenotypeMPUn
immune system phenotypeMPUn
embryogenesis phenotypeMPUn
skeleton phenotypeMPUn
lethality-postnatalMPUn
nervous system phenotypeMPUn
respiratory system phenotypeMPUn
cardiovascular system phenotypeMPUn
limbs/digits/tail phenotypeMPUn
hematopoietic system phenotypeMPUn
reproductive system phenotypeMPUn
hearing/vestibular/ear phenotypeMPUn
growth/size phenotypeMPUn
life span-post-weaning/agingMPUn
liver/biliary system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Hematopoietic cell lineage (04640)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway