IpiRecord: IPI00218252

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cytoplasm	C		ISS
membrane	C		TAS
plasma membrane	C			IDA
cytosol	C		TAS
proteinaceous extracellular matrix	C		TAS
mitochondrion	C			IDA
protein serine/threonine kinase activity	F			ISS
enzyme binding	F			IC
metal ion binding	F		IEA
calcium ion binding	F		NAS
GTP binding	F		NAS	IDA
acyltransferase activity	F		IEA
protein domain specific binding	F			IPI
cysteine-type endopeptidase activity	F		RCA	ISS
transferase activity	F		IEA
protein-glutamine gamma-glutamyltransferase activity	F		IMP	IDA ISS
positive regulation of cell adhesion	P		IMP
G-protein coupled receptor protein signaling pathway	P		TAS
activation of NF-kappaB transcription factor	P			ISS
elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)	P			IMP
release of cytoplasmic sequestered NF-kappaB	P			ISS
histone phosphorylation	P			ISS
induction of apoptosis	P			IDA
positive regulation of inflammatory response	P			IMP
isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	P			IDA
positive regulation of smooth muscle cell proliferation	P			IDA
positive regulation of I-kappaB kinase/NF-kappaB cascade	P			IMP
protein homooligomerization	P			IDA IDA
proteolysis	P		RCA	ISS
blood vessel remodeling	P			IMP
peptide cross-linking	P		TAS	IEA
histone acetylation	P			ISS
protein oligomerization	P			ISS
G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)	P		ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (10)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
behavior/neurological phenotype	MP		Un
immune system phenotype	MP		Un
nervous system phenotype	MP		Un
hematopoietic system phenotype	MP		Un
no phenotypic analysis	MP		Un
life span-post-weaning/aging	MP		Un
abnormal apoptosis	N			ISS
dilated left ventricle	N			ISS

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
Huntington disease pathway	W			IEA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Huntington's disease (05040)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway