IpiRecord: IPI00218419

IPI00218419 - FGFR2, ISOFORM 13 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Uniprot Accession: P21802-13
Uniprot ID: FGFR2_HUMAN
Mapping: Chr 10, 122473377 - 123347962
Entrez Gene: 2263
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1316)
Rat: Fgfr2, SIMILAR TO FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM 2 PRECURSOR.
Mouse: Fgfr2, FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM IIIC.
Mouse: Fgfr2, FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM IIIB.
Rat: Fgfr2, HEPARIN-BINDING FIBROBLAST GROWTH FACTOR RECEPTOR 2 (FRAGMENT).
Rat: Fgfr2, HEPARIN-BINDING FIBROBLAST GROWTH FACTOR RECEPTOR 2 (FRAGMENT).
Rat: Fgfr2, SIMILAR TO FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM IIIB.
Rat: Fgfr2, HEPARIN-BINDING FIBROBLAST GROWTH FACTOR RECEPTOR 2 (FRAGMENT).
Rat: Fgfr2, HEPARIN-BINDING FIBROBLAST GROWTH FACTOR RECEPTOR 2 (FRAGMENT).
Rat: Fgfr2, (KERATINOCYTE GROWTH FACTOR RECEPTOR) ISOFORM 7.
Rat: Fgfr2, (KERATINOCYTE GROWTH FACTOR RECEPTOR) ISOFORM 3.
Rat: Fgfr2, ISOFORM 6.
Rat: Fgfr2, SIMILAR TO FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM IIIB ISOFORM 8.
Rat: Fgfr2, ISOFORM 2.
Rat: Fgfr2, ISOFORM 10.
Human: FGFR2, FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 3 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 5 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 7 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 8 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 9 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 10 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 11 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 12 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 13 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 14 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 15 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 16 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 17 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 18 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 19 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, 79 KDA PROTEIN.
Human: FGFR2, ISOFORM OF FGFR2.
Human: FGFR2, ISOFORM 6 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 4 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, 42 KDA PROTEIN.
Human: FGFR2, FIBROBLAST GROWTH FACTOR RECEPTOR-RELATED PROTEIN.
Human: FGFR2, ISOFORM 20 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.
Human: FGFR2, ISOFORM 2 OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 PRECURSOR.

Annotations for FGFR2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular regionCTAS 
nucleusCIDA IDA ISS 
membraneCIEA IEA ISS 
extracellular spaceCRCA ISS 
integral to membraneCIEA RCA ISS ISS 
kinase activityFIEA 
receptor activityFIEA IEA IEA 
protein-tyrosine kinase activityFIEA IEA IEA ISS IEA 
protein kinase activityFIEA 
protein bindingFIPI ISS 
transferase activityFIEA IEA IEA 
heparin bindingFIEA 
ATP bindingFIEA IEA IEA IEA 
protein serine/threonine kinase activityFISS 
nucleotide bindingFIEA IEA IEA 
fibroblast growth factor receptor activityFIEA ISS TAS ISS 
mesodermal cell differentiationPIEP 
positive regulation of mesenchymal cell proliferationPIGI ISS 
morphogenesis of embryonic epitheliumPIMP ISS 
lung developmentPIGI ISS 
inner ear morphogenesisPIMP 
cell-cell signalingPIMP ISS 
protein amino acid phosphorylationPIEA IEA ISS IEA 
positive regulation of cell proliferationPIMP IGI ISS 
positive regulation of cardiac muscle cell proliferationPIGI 
regulation of cell proliferationPIMP ISS 
embryonic organ morphogenesisPIMP ISS 
epithelial cell proliferationPIMP ISS 
bone mineralizationPIMP ISS 
angiogenesisPIGI ISS 
cell growthPISS 
salivary gland morphogenesisPIMP ISS 
cell fate commitmentPIDA ISS 
fibroblast growth factor receptor signaling pathwayPIGI IGI ISS 
signal transductionPIEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (30)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn Un
cellular phenotypeMPUn
craniofacial phenotypeMPUn Un Un Un Un Un Un Un
homeostasis/metabolism phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn Un Un Un Un
growth/size phenotypeMPUn Un Un Un Un Un Un
immune system phenotypeMPUn Un
embryogenesis phenotypeMPUn Un Un Un Un Un
lethality-embryonic/perinatalMPUn Un Un Un Un Un Un Un
lethality-postnatalMPUn Un Un
muscle phenotypeMPUn Un
skeleton phenotypeMPUn Un Un Un Un Un Un Un
renal/urinary system phenotypeMPUn Un Un Un
nervous system phenotypeMPUn Un Un Un Un
pigmentation phenotypeMPUn
no phenotypic analysisMPUn
respiratory system phenotypeMPUn Un Un Un Un Un
vision/eye phenotypeMPUn Un Un Un Un Un
cardiovascular system phenotypeMPUn Un
digestive/alimentary phenotypeMPUn Un Un Un Un Un
normal phenotypeMPUn Un Un Un
limbs/digits/tail phenotypeMPUn Un Un Un Un
hematopoietic system phenotypeMPUn Un
hearing/vestibular/ear phenotypeMPUn Un Un
reproductive system phenotypeMPUn Un Un Un
liver/biliary system phenotypeMPUn
touch/vibrissae phenotypeMPUn
embryonic lethalityNIEA
abnormal limb bud morphologyNIEA
abnormal lung developmentNIEA

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway