IpiRecord: IPI00218768

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
nucleus	C			IDA IDA IDA
cytoplasm	C			IMP IDA IDA
mitochondrion	C		IDA	ISS
soluble fraction	C		IDA	ISS
nucleotide binding	F		IEA	IEA
protein binding	F		IPI	ISS ISS IPI IMP
glucose binding	F			ISS IDA
kinase activity	F		IEA	IEA
ATP binding	F		IEA IEA	ISS IEA
glucokinase activity	F		IMP IMP IDA IDA IMP IDA IMP	IDA ISS ISS IDA
transferase activity	F		IEA	IEA
hexokinase activity	F		IEA
glucose 6-phosphate metabolic process	P			IDA
carbohydrate phosphorylation	P		IMP IDA IMP IDA	IDA
glucose metabolic process	P		IDA IDA IMP IMP IMP
regulation of insulin secretion	P		IMP IMP
cell glucose homeostasis	P		IMP	TAS ISS IMP
regulation of potassium ion transport	P		IMP
NADP metabolic process	P		IMP
glucose homeostasis	P		IMP IMP IMP IMP
glycolysis	P		IEA IEA	IEA
positive regulation of insulin secretion	P		IMP
second-messenger-mediated signaling	P			IDA
response to glucose stimulus	P			IEP

Cellular Component

Biological Process

Molecular Function

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
endocrine/exocrine gland phenotype	MP		Un Un Un
homeostasis/metabolism phenotype	MP		Un Un Un Un Un Un Un Un
lethality-embryonic/perinatal	MP		Un Un
lethality-postnatal	MP		Un Un Un Un Un
renal/urinary system phenotype	MP		Un Un
digestive/alimentary phenotype	MP		Un Un Un
hematopoietic system phenotype	MP		Un
growth/size phenotype	MP		Un Un
liver/biliary system phenotype	MP		Un Un Un Un

Disease (6)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Diabetes Mellitus	D			ISS
Hypoglycemia	D			ISS
Diabetes Mellitus, Non-Insulin-Dependent	D			ISS
Diabetes, Gestational	D			ISS
Hyperinsulinism	D			ISS
Hypertension	D			ISS

Pathway (8)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
galactose metabolic pathway	W			IEA
glycogen metabolic pathway	W			IDAIDA
aminosugars metabolic pathway	W			IEA
glycogen biosynthetic pathway	W			IDA
glycolysis/gluconeogenesis pathway	W			IEA
streptomycin biosynthetic pathway	W			IEA
starch and sucrose metabolic pathway	W			IEA
fructose and mannose metabolic pathway	W			IEA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Glycolysis / Gluconeogenesis (00010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Galactose metabolism (00052)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Type II diabetes mellitus (04930)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Starch and sucrose metabolism (00500)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Streptomycin biosynthesis (00521)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Insulin signaling pathway (04910)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Maturity onset diabetes of the young (04950)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway