IpiRecord: IPI00219084

IPI00219084 - RELA, ISOFORM 2 OF TRANSCRIPTION FACTOR P65.
Uniprot Accession: Q04206-2
Uniprot ID: TF65_HUMAN
Mapping: Chr 11, 65177649 - 65186959
Entrez Gene: 5970
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1713)
Rat: Rela, RELA.
Mouse: Rela, ISOFORM P65 OF TRANSCRIPTION FACTOR P65.
Mouse: Rela, ISOFORM P65 DELTA OF TRANSCRIPTION FACTOR P65.
Mouse: Rela, NF-KB RELA SPLICE VARIANT 1.
Rat: Rela, 59 KDA PROTEIN.
Rat: Rela, NUCLEAR FACTOR KAPPA B SUBUNIT P65 (FRAGMENT).
Human: RELA, RELA PROTEIN.
Human: RELA, ISOFORM 2 OF TRANSCRIPTION FACTOR P65.
Human: RELA, ISOFORM 1 OF TRANSCRIPTION FACTOR P65.
Human: RELA, ISOFORM 3 OF TRANSCRIPTION FACTOR P65.

Annotations for RELA and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nucleusCIEA IDA IDA ISS IDA IEA ISS 
cytoplasmCIDA IDA ISS ISS 
RNA polymerase II transcription factor activity, enhancer bindingFIDA 
transcription activator activityFTAS ISS 
signal transducer activityFIEP 
transcription factor activityFIEA IDA IEA ISS 
protein kinase activityFIDA ISS 
protein bindingFIPI IPI ISS 
DNA bindingFIDA IDA ISS IDA IDA IDA IDA ISS 
positive regulation of interleukin-12 biosynthetic processPIDA ISS 
regulation of transcriptionPIEA 
hair follicle developmentPIMP ISS 
activation of NF-kappaB transcription factorPISS 
defense responsePIMP ISS 
liver developmentPIMP 
regulation of transcription, DNA-dependentPIEA IEA IEA IEA 
organ morphogenesisPIMP ISS 
positive regulation of transcription, DNA-dependentPIDA ISS 
transcriptionPIEA 
positive regulation of I-kappaB kinase/NF-kappaB cascadePIEP 
negative regulation of protein catabolic processPIMP ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (11)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
cellular phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
respiratory system phenotypeMPUn
digestive/alimentary phenotypeMPUn
life span-post-weaning/agingMPUn
growth/size phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Epithelial cell signaling in Helicobacter pylori infection (05120)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adipocytokine signaling pathway (04920)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway