| IPI00219307 - CASP1, ISOFORM BETA OF CASPASE-1 PRECURSOR. | |
|---|---|
| Uniprot Accession: P29466-2 | |
| Uniprot ID: CASP1_HUMAN | |
| Mapping: Chr 11, 104401458 - 104477368 | |
| Entrez Gene: 834 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7623) |
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| Rat: Casp1, CASPASE-1 PRECURSOR. |
| Mouse: Casp1, CASPASE-1 PRECURSOR. |
| Human: CASP1, ISOFORM ALPHA OF CASPASE-1 PRECURSOR. |
| Human: CASP1, ISOFORM BETA OF CASPASE-1 PRECURSOR. |
| Human: CASP1, ISOFORM GAMMA OF CASPASE-1 PRECURSOR. |
| Human: CASP1, ISOFORM DELTA OF CASPASE-1 PRECURSOR. |
| Human: CASP1, ISOFORM EPSILON OF CASPASE-1 PRECURSOR. |
| Human: INCA, INCA. |
| Human: CASP1, CASP1 NIRS VARIANT 1. |
| Human: CASP1, 43 KDA PROTEIN. |
| Human: CASP1, ISOFORM ZETA OF CASPASE-1 PRECURSOR. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| intracellular | C | IEA | IEA | IEA |
| cytoplasm | C | TAS | ISS | |
| extracellular region | C | IDA | ISS IEA | |
| caspase activator activity | F | ISS | ||
| peptidase activity | F | IEA | ||
| hydrolase activity | F | IEA | ||
| signal transducer activity | F | ISS | ||
| protein binding | F | IEA | IPI IPI | ISS ISS IEA |
| cysteine-type peptidase activity | F | IEA | IEA | IEA |
| caspase activity | F | IEA | IEA | ISS ISS IEA |
| catalytic activity | F | IEA | ||
| metabolic process | P | IEA | ||
| apoptosis | P | IEA | IEP | |
| response to hypoxia | P | IMP | ISS IEA | |
| induction of apoptosis | P | IDA IMP IEA | ISS IEA | |
| cell death | P | IDA | ISS IEA | |
| regulation of apoptosis | P | IEA | IEA | IEA |
| positive regulation of I-kappaB kinase/NF-kappaB cascade | P | ISS | ||
| protein processing | P | IDA IMP | ISS IEA | |
| signal transduction | P | ISS | ||
| proteolysis | P | IEA | IEA | ISS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| immune system phenotype | MP | Un Un | ||
| renal/urinary system phenotype | MP | Un | ||
| nervous system phenotype | MP | Un | ||
| tumorigenesis | MP | Un | ||
| hematopoietic system phenotype | MP | Un | ||
| reproductive system phenotype | MP | Un |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| programmed cell death pathway | W | IEA | ||
| mitogen activated protein kinase signaling pathway | W | IEA | ||
| Huntington disease pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Huntington's disease (05040) | Present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Dentatorubropallidoluysian atrophy (DRPLA) (05050) | Present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Neurodegenerative Disorders (01510) | Present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |