IpiRecord: IPI00219563

IPI00219563 - PLCB1, BETA-1.
Uniprot Accession: Q9NQ66-1
Uniprot ID: PLCB1_HUMAN
Mapping: Chr 20, 8060908 - 8813547
Entrez Gene: 23236
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3837)
Rat: Plcb1, 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-1.
Mouse: Plcb1, BETA-1.
Mouse: Plcb1, BETA-1.
Mouse: Plcb1, PLCB1 PROTEIN.
Mouse: Plcb1, PHOSPHOLIPASE C, BETA 1.
Rat: Plcb1, 133 KDA PROTEIN.
Human: PLCB1, PHOSPHOLIPASE C, BETA 1.
Human: PLCB1, PHOSPHOLIPASE C, BETA 1.
Human: PLCB1, BETA-1.
Human: PLCB1, BETA-1.
Human: PLCB1, PHOSPHOLIPASE C, BETA 1.

Annotations for PLCB1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytosolCIDA 
cytoplasmCISS ISS 
nucleusCISS 
membrane fractionCIDA 
hydrolase activityFRCA ISS IEA 
calcium ion bindingFIEA IEA IEA 
signal transducer activityFRCA ISS IEA 
phospholipase C activityFRCA ISS 
phosphoinositide phospholipase C activityFRCA ISS ISS IDA IEA 
regulation of progression through cell cyclePISS 
lipid metabolic processPRCA ISS 
intracellular signaling cascadePRCA ISS IEA 
phosphoinositide metabolic processPIEP 
learningPIEP 
lipid catabolic processPRCA ISS IEA 
memoryPIEP 
oxygen and reactive oxygen species metabolic processPIEP 
signal transductionPRCA ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
behavior/neurological phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
lethality-postnatalMPUn
nervous system phenotypeMPUn
growth/size phenotypeMPUn
depression-related behaviorNIED

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
CardiomegalyDIED

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
inositol metabolic pathwayWIEA
valine, leucine and isoleucine degradation pathwayWIEA
propanoate metabolic pathwayWIEA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
GnRH signaling pathway (04912)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term depression (04730)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Calcium signaling pathway (04020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Inositol phosphate metabolism (00562)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term potentiation (04720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Phosphatidylinositol signaling system (04070)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway