IpiRecord: IPI00219689

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
plasma membrane	C		IDA
cytoplasm	C		IDA
intracellular	C		IEA	IEA
epidermal growth factor receptor binding	F		IPI
metal ion binding	F		IEA
diacylglycerol binding	F		IEA
zinc ion binding	F		IEA
guanyl-nucleotide exchange factor activity	F		IMP	IEA
Rho guanyl-nucleotide exchange factor activity	F		IGI	IEA
Rac guanyl-nucleotide exchange factor activity	F		IGI
intracellular signaling cascade	P	IEA	IEA	IEA
regulation of Rho protein signal transduction	P		IEA	IEA
positive regulation of phosphoinositide 3-kinase activity	P		IGI
positive regulation of cell adhesion	P		IGI
vesicle fusion	P		IGI
cell projection biogenesis	P		IGI
integrin-mediated signaling pathway	P		IGI
lamellipodium biogenesis	P		IGI
regulation of GTPase activity	P		IGI
cell migration	P		IGI
small GTPase mediated signal transduction	P		IMP

Cellular Component

Biological Process

Molecular Function

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
homeostasis/metabolism phenotype	MP		Un
immune system phenotype	MP		Un
muscle phenotype	MP		Un
renal/urinary system phenotype	MP		Un
nervous system phenotype	MP		Un
cardiovascular system phenotype	MP		Un
hematopoietic system phenotype	MP		Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (7)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
T cell receptor signaling pathway (04660)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
B cell receptor signaling pathway (04662)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Fc epsilon RI signaling pathway (04664)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Leukocyte transendothelial migration (04670)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Regulation of actin cytoskeleton (04810)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway