IpiRecord: IPI00219761

IPI00219761 - PPARD, ISOFORM 2 OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA.
Uniprot Accession: Q03181-2
Uniprot ID: PPARD_HUMAN
Mapping: Chr 6, 35418320 - 35503933
Entrez Gene: 5467
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14346)
Rat: Ppard, PPAR DELTA PROTEIN.
Mouse: Ppard, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA.
Human: PPARD, ISOFORM 1 OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA.
Human: PPARD, ISOFORM 2 OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA.

Annotations for PPARD and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nucleusCIEA IEA ISS IEA NAS 
transcription repressor activityFIDA ISS 
NF-kappaB bindingFIPI 
metal ion bindingFIEA IEA 
retinoid X receptor bindingFTAS 
protein heterodimerization activityFTAS 
prostacyclin receptor activityFTAS 
steroid hormone receptor activityFIEA ISS IEA 
DNA bindingFIDA ISS 
enzyme activator activityFTAS 
transcription factor activityFIEA ISS IEA TAS 
sequence-specific DNA bindingFIEA IEA 
receptor activityFIEA 
fatty acid bindingFISS IDA 
ligand-dependent nuclear receptor activityFTAS ISS TAS 
zinc ion bindingFIEA IEA IEA 
cholesterol metabolic processPISS 
response to temperature stimulusPNAS 
anagenPIMP ISS 
positive regulation of phosphoinositide 3-kinase cascadePIDA ISS 
fatty acid catabolic processPISS 
negative regulation of I-kappaB kinase/NF-kappaB cascadePNAS 
fatty acid oxidationPIDA 
lipid metabolic processPIMP IMP NAS ISS NAS 
generation of precursor metabolites and energyPISS 
glucose metabolic processPISS 
decidualizationPISS 
cell differentiationPIDA IMP ISS 
cell proliferationPIMP ISS ISS 
apoptosisPISS 
vitamin A metabolic processPIMP 
positive regulation of fat cell differentiationPISS 
embryo implantationPTAS TAS ISS 
fatty acid transportPIEP ISS 
regulation of insulin secretionPNAS 
cellular processPTAS 
glucose transportPISS 
axon ensheathmentPIMP ISS 
epidermis developmentPTAS ISS 
transcriptionPIEA IEA 
response to painPNAS 
fatty acid beta-oxidationPIEP ISS ISS 
regulation of transcription, DNA-dependentPIEA IEA IEA 
negative regulation of transcription from RNA polymerase II promoterPIDA ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (14)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn Un Un
adipose tissue phenotypeMPUn Un
homeostasis/metabolism phenotypeMPUn Un Un
behavior/neurological phenotypeMPUn
immune system phenotypeMPUn
embryogenesis phenotypeMPUn Un Un
lethality-embryonic/perinatalMPUn Un Un Un Un
nervous system phenotypeMPUn Un
touch/vibrissae phenotypeMPUn
tumorigenesisMPUn Un
digestive/alimentary phenotypeMPUn Un
reproductive system phenotypeMPUn
liver/biliary system phenotypeMPUn
growth/size phenotypeMPUn Un Un

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
ObesityDISS
Diabetes Mellitus, Non-Insulin-DependentDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
PPAR signaling pathway (03320)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway