IpiRecord: IPI00219896

IPI00219896 - ITGAL, ISOFORM 2 OF INTEGRIN ALPHA-L PRECURSOR.
Uniprot Accession: P20701-2
Uniprot ID: ITAL_HUMAN
Mapping: Chr 16, 30391551 - 30441772
Entrez Gene: 3683
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1240)
Rat: Itgal, INTEGRIN ALPHA L.
Mouse: Itgal, INTEGRIN ALPHA-L PRECURSOR.
Mouse: Itgal, CLONE:C630032K18 PRODUCT:INTEGRIN ALPHA L, FULL INSERT SEQUENCE.
Mouse: Itgal, CLONE:F830013L17 PRODUCT:INTEGRIN ALPHA L, FULL INSERT SEQUENCE.
Human: ITGAL, ISOFORM 1 OF INTEGRIN ALPHA-L PRECURSOR.
Human: ITGAL, ISOFORM 2 OF INTEGRIN ALPHA-L PRECURSOR.
Human: ITGAL, ITGAL PROTEIN.

Annotations for ITGAL and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integrin complexCIEA IEA ISS IEA 
integral to membraneCIEA RCA ISS IEA 
membraneCIEA 
cell surfaceCIDA 
immunological synapseCIDA 
plasma membraneCIEA 
calcium ion bindingFIEA 
magnesium ion bindingFIEA 
protein heterodimerization activityFIPI 
receptor activityFIEA IEA IEA 
protein bindingFIEA IEA IEA 
cell-cell adhesionPIMP 
leukocyte adhesionPIDA 
signal transductionPISS 
integrin-mediated signaling pathwayPIEA IEA IEA 
cell adhesionPIEA IEA IEA ISS IEA 
activated T cell proliferationPIMP ISS 
inflammatory responsePISS 
cell motilityPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMPUn Un Un
hematopoietic system phenotypeMPUn Un Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
integrin signaling pathwayWISS

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cell adhesion molecules (CAMs) (04514)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway