| IPI00220267 - ASL, ARGININOSUCCINATE LYASE. | |
|---|---|
| Uniprot Accession: P04424 | |
| Uniprot ID: ARLY_HUMAN | |
| Mapping: Chr 7, 65178211 - 65195756 | |
| Entrez Gene: 435 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10974) |
|---|
| Rat: Asl, ARGININOSUCCINATE LYASE. |
| Mouse: Asl, ARGININOSUCCINATE LYASE. |
| Human: ASL, ARGININOSUCCINATE LYASE. |
| Human: ASL, 50 KDA PROTEIN. |
| Human: ASL, ARGININOSUCCINATE LYASE ISOFORM 2. |
| Human: ASL, ARGININOSUCCINATE LYASE ISOFORM 3. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | TAS | RCA | ISS ISS IDA |
| lyase activity | F | IEA | RCA | ISS IEA |
| catalytic activity | F | IEA | RCA | ISS |
| argininosuccinate lyase activity | F | TAS IEA | RCA | ISS ISS ISS IDA IEA |
| response to peptide hormone stimulus | P | IEP | ||
| argininosuccinate metabolic process | P | IDA | ||
| urea cycle | P | IEA | RCA | NAS ISS IEA |
| response to glucocorticoid stimulus | P | IEP | ||
| response to steroid hormone stimulus | P | IEP | ||
| arginine catabolic process | P | TAS | RCA | ISS ISS |
| response to hypoxia | P | IEP | ||
| response to nutrient | P | IEP | ||
| amino acid biosynthetic process | P | IEA | IEA | IEA |
| response to cAMP | P | IEP | ||
| arginine biosynthetic process via ornithine | P | IEA | IEA | IEA |
| arginine biosynthetic process | P | RCA | NAS ISS | |
| kidney development | P | IEP | ||
| liver development | P | IEP IDA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| behavior/neurological phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| lethality-postnatal | MP | Un | ||
| increased circulating ammonia level | N | ISS |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Endotoxemia | D | IEP | ||
| Reperfusion Injury | D | IEP | ||
| Hyperammonemia | D | IEP |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| alanine and aspartate metabolic pathway | W | IEA | ||
| arginine and proline metabolic pathway | W | IEA | ||
| pathway of urea cycle and metabolism of amino groups | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Arginine and proline metabolism (00330) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Alanine and aspartate metabolism (00252) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Urea cycle and metabolism of amino groups (00220) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |