| IPI00221301 - CTH, ISOFORM 2 OF CYSTATHIONINE GAMMA-LYASE. | |
|---|---|
| Uniprot Accession: P32929-2 | |
| Uniprot ID: CGL_HUMAN | |
| Mapping: Chr 1, 70649543 - 70677841 | |
| Entrez Gene: 1491 | |
| Entrez MapView: |
|
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2942) |
|---|
| Rat: Cth, CYSTATHIONINE GAMMA-LYASE. |
| Mouse: Cth, CYSTATHIONINE GAMMA-LYASE. |
| Human: CTH, ISOFORM 1 OF CYSTATHIONINE GAMMA-LYASE. |
| Human: CTH, ISOFORM 2 OF CYSTATHIONINE GAMMA-LYASE. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular_component | C | ND | ND | |
| cytoplasm | C | IEA | ||
| catalytic activity | F | IEA | ||
| lyase activity | F | IEA | IEA | |
| cystathionine gamma-lyase activity | F | IDA | ISS ISS IEA | |
| cystathionine beta-lyase activity | F | IDA | ||
| pyridoxal phosphate binding | F | IEA | TAS IEA | |
| negative regulation of cell proliferation | P | IMP | ||
| glutathione metabolic process | P | IMP | ||
| cysteine biosynthetic process | P | IEA | IDA IEA | |
| amino acid biosynthetic process | P | IEA | IEA | |
| amino acid metabolic process | P | IEA | ||
| negative regulation of cell growth | P | IMP | ||
| homocysteine metabolic process | P | IDA | ||
| transsulfuration | P | TAS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Amino Acid Metabolism, Inborn Errors | D | ISS | ||
| Cataract | D | IED |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| methionine cycle/metabolic pathway | W | IEA | ||
| cysteine metabolic pathway | W | IEA IDA | ||
| nitrogen metabolic pathway | W | IEA | ||
| selenoamino acid metabolic pathway | W | IEA | ||
| glycine, serine and threonine metabolic pathway | W | IEA | ||
| transulfuration pathway of homocysteine metabolism | W | IDA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glycine, serine and threonine metabolism (00260) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Methionine metabolism (00271) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Selenoamino acid metabolism (00450) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cysteine metabolism (00272) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Nitrogen metabolism (00910) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |