IPI report for IPI00221307

IpiRecord: IPI00221307

IPI00221307 - CASP7, ISOFORM ALPHA OF CASPASE-7 PRECURSOR.
Uniprot Accession: Q5SVL0
Uniprot ID: Q5SVL0_HUMAN
Mapping: Chr 10, 115428953 - 115480652
Entrez Gene: 840
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: P55210-1 UniProtKB/Swiss-Prot: CASP7_HUMAN Vega: OTTHUMP00000020510 Vega: OTTHUMP00000020511 Vega: OTTHUMP00000020514 ENSEMBL_HAVANA: ENSP00000298701 ENSEMBL_HAVANA: ENSG00000165806 ENSEMBL_HAVANA: ENSP00000358321 ENSEMBL_HAVANA: ENSG00000165806 ENSEMBL_HAVANA: ENSP00000358324 ENSEMBL_HAVANA: ENSG00000165806 REFSEQ_REVIEWED: NP_001218 REFSEQ_REVIEWED: GI:4502581 REFSEQ_REVIEWED: NP_203125 REFSEQ_REVIEWED: GI:15718700 UniProtKB/TrEMBL: Q5SVL0 UniProtKB/TrEMBL: Q5SVL0_HUMAN ENSEMBL: ENSP00000358327 ENSEMBL: ENSG00000165806 UniParc: UPI000003AEFD HGNC: 1508 Entrez Gene: 840 UniGene: Hs.9216 CCDS: CCDS7581.1 UTRdb: BB002365 UTRdb: BB002415 UTRdb: BB009887 UTRdb: BB073328 UTRdb: BB280277 RZPD: Hs.9216 InterPro: IPR015471 InterPro: IPR001309 InterPro: IPR011600 InterPro: IPR002138 InterPro: IPR002398 InterPro: IPR015917 Pfam: PF00656 PRINTS: PR00376 SMART: SM00115 PROSITE: PS01122 PROSITE: PS01121 PROSITE: PS50207 PROSITE: PS50208 PANTHER: PTHR10454:SF31 PANTHER: PTHR10454

IPI00221307 - CASP7, ISOFORM ALPHA OF CASPASE-7 PRECURSOR.

Uniprot Accession: Q5SVL0

Uniprot ID: Q5SVL0_HUMAN

Mapping: Chr 10, 115428953 - 115480652

Entrez Gene: 840

Entrez MapView: Geneprod

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1968)
Rat: Casp7, CASPASE-7.
Mouse: Casp7, CASPASE-7 PRECURSOR.
Human: CASP7, ISOFORM BETA OF CASPASE-7 PRECURSOR.
Human: CASP7, ISOFORM ALPHA' OF CASPASE-7 PRECURSOR.
Human: CASP7, ISOFORM ALPHA OF CASPASE-7 PRECURSOR.
Human: CASP7, UNCHARACTERIZED PROTEIN CASP7.
Human: CASP7, CASPASE 7, APOPTOSIS-RELATED CYSTEINE PEPTIDASE.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1968)

Rat: Casp7, CASPASE-7.

Mouse: Casp7, CASPASE-7 PRECURSOR.

Human: CASP7, ISOFORM BETA OF CASPASE-7 PRECURSOR.

Human: CASP7, ISOFORM ALPHA' OF CASPASE-7 PRECURSOR.

Human: CASP7, ISOFORM ALPHA OF CASPASE-7 PRECURSOR.

Human: CASP7, UNCHARACTERIZED PROTEIN CASP7.

Human: CASP7, CASPASE 7, APOPTOSIS-RELATED CYSTEINE PEPTIDASE.

Annotations for CASP7 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
endoplasmic reticulum membrane	C			ISS
cytoplasm	C		IEA	ISS
mitochondrial membrane	C			ISS
protein binding	F			ISS
peptidase activity	F		IEA
hydrolase activity	F		IEA
cysteine-type peptidase activity	F	IEA	IEA	ISS IEA
caspase activity	F	IEA	RCA IDA	ISS ISS IEA IDA
response to UV	P		IGI	ISS
apoptosis	P	IEA	IEA	TAS
regulation of apoptosis	P		RCA	ISS
induction of apoptosis	P		IGI RCA IEA	ISS
heart development	P		IGI	ISS
apoptotic program	P			ISS
proteolysis	P	IEA	RCA	ISS ISS IEA IDA
release of cytochrome c from mitochondria	P		IGI	ISS

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
lethality-embryonic/perinatal	MP		Un
vision/eye phenotype	MP		Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Alzheimer's disease (05010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Apoptosis (04210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Dentatorubropallidoluysian atrophy (DRPLA) (05050)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Neurodegenerative Disorders (01510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway