IpiRecord: IPI00237671

IPI00237671 - NEFL, NEUROFILAMENT LIGHT POLYPEPTIDE.
Uniprot Accession: P07196
Uniprot ID: NFL_HUMAN
Mapping: Chr 8, 24866240 - 24869946
Entrez Gene: 4747
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12418)
Rat: Nefl, NEUROFILAMENT LIGHT POLYPEPTIDE.
Mouse: Nefl, NEUROFILAMENT LIGHT POLYPEPTIDE.
Human: NEFL, PUTATIVE UNCHARACTERIZED PROTEIN DKFZP761K0922.
Human: NEFL, NEUROFILAMENT LIGHT POLYPEPTIDE.
Human: NEFL, NEFL PROTEIN.
Human: NEFL, 33 KDA PROTEIN.

Annotations for NEFL and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
axonCIDA IDA 
neuron projectionCIDA 
neurofilamentCTAS IDA IDA IDA NAS 
intermediate filamentCIEA IEA IDA IEA 
structural molecule activityFIEA IEA IEA 
protein bindingFIPI IPI IPI IPI IDA ISS IEA 
structural constituent of cytoskeletonFTAS 
protein domain specific bindingFIPI 
phospholipase bindingFIPI 
intermediate filament organizationPIMP IMP 
regulation of axon diameterPIMP IMP 
locomotionPIMP 
axon regeneration in the peripheral nervous systemPIMP 
neurofilament cytoskeleton organization and biogenesisPIMP IGI IMP IMP IGI IGI IMP IMP 
negative regulation of neuron apoptosisPIMP IMP 
intermediate filament cytoskeleton organization and biogenesisPISS IEA 
microtubule cytoskeleton organization and biogenesisPIMP 
neurite morphogenesisPIMP 
intermediate filament bundle assemblyPIGI 
regulation of balancePIMP 
positive regulation of axonogenesisPIMP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (1)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
nervous system phenotypeMPUn

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Charcot-Marie-Tooth DiseaseDISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
amyotrophic lateral sclerosis disease pathwayWIEA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Amyotrophic lateral sclerosis (ALS) (05030)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway