| IPI00247063 - MME, NEPRILYSIN. | |
|---|---|
| Uniprot Accession: P08473 | |
| Uniprot ID: NEP_HUMAN | |
| Mapping: Chr 3, 156284651 - 156384186 | |
| Entrez Gene: 4311 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2432) |
|---|
| Rat: Mme, NEPRILYSIN. |
| Mouse: Mme, NEPRILYSIN. |
| Human: MME, NEPRILYSIN. |
| Human: MME, MME PROTEIN. |
| Human: MME, 9 KDA PROTEIN. |
| Human: MME, 4 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integral to plasma membrane | C | TAS | ISS | |
| plasma membrane | C | TAS | IMP ISS | |
| membrane fraction | C | IDA | ||
| membrane | C | IEA | IDA | ISS IEA |
| integral to membrane | C | RCA | ISS IEA | |
| metallopeptidase activity | F | TAS | IEA IEA | ISS IEA |
| zinc ion binding | F | IEA | IEA IEA | IEA |
| protein binding | F | IPI | ||
| peptide binding | F | IMP IDA | ||
| neprilysin activity | F | IEA | IDA | IMP ISS IEA IDA |
| metal ion binding | F | IEA | IEA | IEA |
| peptidase activity | F | IEA | ||
| hydrolase activity | F | IEA | ||
| peptide metabolic process | P | IMP | ||
| proteolysis | P | TAS IEA | IEA | IMP ISS IDA IEA |
| cell-cell signaling | P | TAS | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| liver/biliary system phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Glomerulonephritis, Membranous | D | ISS | ||
| Cerebral Amyloid Angiopathy | D | ISS | ||
| Alzheimer Disease | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| renin-angiotensin system signaling pathway | W | ISSISSIMP | ||
| angiotensin (1-7) signaling pathway | W | ISSISSIMP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Alzheimer's disease (05010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Hematopoietic cell lineage (04640) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |