| IPI00288947 - GNAQ, GUANINE NUCLEOTIDE BINDING PROTEIN. | |
|---|---|
| Uniprot Accession: Q6NT27 | |
| Uniprot ID: Q6NT27_HUMAN | |
| Mapping: Chr 9, 79520823 - 79836194 | |
| Entrez Gene: 2776 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1565) |
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| Rat: Gnaq, GUANINE NUCLEOTIDE BINDING PROTEIN, ALPHA Q POLYPEPTIDE. |
| Mouse: Gnaq, INSERT SEQUENCE. |
| Human: GNAQ, GUANINE NUCLEOTIDE BINDING PROTEIN. |
| Human: GNAQ, GUANINE NUCLEOTIDE BINDING PROTEIN (G PROTEIN), Q POLYPEPTIDE. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| caveolar membrane | C | IDA | ||
| plasma membrane | C | TAS TAS | ISS | |
| cytoplasm | C | TAS | ISS | |
| heterotrimeric G-protein complex | C | NR | TAS TAS | TAS ISS ISS |
| caveola | C | IDA | ||
| guanyl nucleotide binding | F | IEA | IEA | |
| nucleotide binding | F | IEA | IEA | IEA |
| GTPase activity | F | TAS | TAS TAS | ISS ISS TAS |
| signal transducer activity | F | IEA | IEA IEA | IEA |
| GTP binding | F | IEA IEA | IEA IEA | IEA |
| G-protein coupled receptor protein signaling pathway | P | IEA | IMP | ISS IEA |
| anti-apoptosis | P | IMP | ||
| signal transduction | P | IEA | IEA IEA | IEA |
| heart development | P | IEA | IMP | ISS IEA |
| positive regulation of apoptosis | P | TAS | ||
| embryonic digit morphogenesis | P | IEA | IGI | ISS IEA |
| phospholipase C activation | P | TAS | ISS IMP | |
| regulation of melanocyte differentiation | P | IEA | IMP | ISS IEA |
| protein amino acid ADP-ribosylation | P | IEA | RCA | ISS IEA |
| neuron remodeling | P | IEA | IMP | ISS IEA |
| G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) | P | IMP | ||
| regulation of action potential | P | IEA | IMP | ISS IEA |
| G-protein signaling, adenylate cyclase activating pathway | P | IEA | IDA | ISS IEA |
| positive regulation of smooth muscle cell proliferation | P | IMP | ||
| negative regulation of potassium ion transport | P | IMP | ||
| skeletal development | P | IEA | IMP | ISS IEA |
| blood coagulation | P | TAS | ISS | |
| glutamate signaling pathway | P | IEA | IMP | ISS IEA |
| dopamine receptor, phospholipase C activating pathway | P | IGI | ||
| pigmentation during development | P | IEA | IMP | ISS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| craniofacial phenotype | MP | Un Un | ||
| pigmentation phenotype | MP | Un | ||
| behavior/neurological phenotype | MP | Un Un | ||
| homeostasis/metabolism phenotype | MP | Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un | ||
| skeleton phenotype | MP | Un | ||
| muscle phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un | ||
| nervous system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un | ||
| hematopoietic system phenotype | MP | Un Un | ||
| respiratory system phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un Un | ||
| normal phenotype | MP | Un | ||
| limbs/digits/tail phenotype | MP | Un | ||
| hearing/vestibular/ear phenotype | MP | Un Un | ||
| touch/vibrissae phenotype | MP | Un | ||
| abnormal cardiovascular system morphology | N | ISS | ||
| embryonic lethality | N | ISS | ||
| abnormal craniofacial morphology | N | ISS | ||
| perinatal lethality | N | ISS |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Cardiomegaly | D | ISS | ||
| Cardiomyopathy, Congestive | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| G protein signaling pathway via Galphaq family | W | IMP | ||
| orexin/hypocretin signaling pathway through the orexin/hypocretin receptor 1 | W | IMP | ||
| orexin/hypocretin signaling pathway through the orexin/hypocretin receptor 2 | W | IMP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| GnRH signaling pathway (04912) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Long-term depression (04730) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Calcium signaling pathway (04020) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Gap junction (04540) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Long-term potentiation (04720) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |