IPI report for IPI00289758

IpiRecord: IPI00289758

IPI00289758 - CAPN2, CALPAIN-2 CATALYTIC SUBUNIT PRECURSOR.
Uniprot Accession: Q59EF6
Uniprot ID: Q59EF6_HUMAN
Mapping: Chr 1, 221966657 - 222030343
Entrez Gene: 824
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: P17655 UniProtKB/Swiss-Prot: CAN2_HUMAN Vega: OTTHUMP00000035497 ENSEMBL_HAVANA: ENSP00000355834 ENSEMBL_HAVANA: ENSG00000162909 REFSEQ_REVIEWED: NP_001739 REFSEQ_REVIEWED: GI:157389005 UniProtKB/TrEMBL: A6NDG7 UniProtKB/TrEMBL: A6NDG7_HUMAN UniProtKB/TrEMBL: Q59EF6 UniProtKB/TrEMBL: Q59EF6_HUMAN ENSEMBL: ENSP00000295006 ENSEMBL: ENSG00000162909 H-InvDB: HIT000194882 UniParc: UPI0000169FBE HGNC: 1479 Entrez Gene: 824 UniGene: Hs.350899 CCDS: CCDS31035.1 trome: HTR002587 Transfac: G000222 UTRdb: BB003725 UTRdb: BB084096 UTRdb: BB259056 UTRdb: BB275080 UTRdb: BB278603 UTRdb: BB281721 UTRdb: BB385851 UTRdb: CC290074 RZPD: Hs.350899 CleanEx: HS_CAPN2 InterPro: IPR011992 InterPro: IPR002048 InterPro: IPR000169 InterPro: IPR001300 Pfam: PF01067 Pfam: PF00036 Pfam: PF00648 PRINTS: PR00704 SMART: SM00720 SMART: SM00230 SMART: SM00054 PROSITE: PS50203 PROSITE: PS00018 PROSITE: PS50222 PROSITE: PS00139 SUPERFAMILY: SSF49758 GENE3D: G3DSA:1.10.238.10

IPI00289758 - CAPN2, CALPAIN-2 CATALYTIC SUBUNIT PRECURSOR.

Uniprot Accession: Q59EF6

Uniprot ID: Q59EF6_HUMAN

Mapping: Chr 1, 221966657 - 222030343

Entrez Gene: 824

Entrez MapView: Geneprod

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11567)
Rat: Capn2, CALPAIN-2 CATALYTIC SUBUNIT PRECURSOR.
Mouse: Capn2, CALPAIN-2 CATALYTIC SUBUNIT PRECURSOR.
Mouse: Capn2, CLONE:D230050I17 PRODUCT:CALPAIN 2, FULL INSERT SEQUENCE.
Human: CAPN2, CALPAIN-2 CATALYTIC SUBUNIT PRECURSOR.
Human: CAPN2, 14 KDA PROTEIN.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11567)

Rat: Capn2, CALPAIN-2 CATALYTIC SUBUNIT PRECURSOR.

Mouse: Capn2, CALPAIN-2 CATALYTIC SUBUNIT PRECURSOR.

Mouse: Capn2, CLONE:D230050I17 PRODUCT:CALPAIN 2, FULL INSERT SEQUENCE.

Human: CAPN2, CALPAIN-2 CATALYTIC SUBUNIT PRECURSOR.

Human: CAPN2, 14 KDA PROTEIN.

Annotations for CAPN2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
membrane	C	IEA	IEA
cytoplasm	C	IEA	IEA	TAS
intracellular	C	IEA	IEA	IEA
peptidase activity	F		IEA
cysteine-type endopeptidase activity	F		IEA
cysteine-type peptidase activity	F		IEA
calcium ion binding	F	IEA	IEA IEA	IDA IEA
hydrolase activity	F		IEA
protein binding	F	IPI		IPI
calcium-dependent cysteine-type endopeptidase activity	F	IEA	TAS	IDA IPI ISS IEA
response to hypoxia	P			IEP
myoblast fusion	P		IMP	IEA
proteolysis	P	IEA	IEA	TAS IEA

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
other phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
the proteolytic pathway involving calcium-dependent proteases	W			IDA

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Apoptosis (04210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway