IpiRecord: IPI00290198

IPI00290198 - IL18, INTERLEUKIN-18 PRECURSOR.
Uniprot Accession: Q96KJ8
Uniprot ID: Q96KJ8_HUMAN
Mapping: Chr 11, 111519186 - 111540050
Entrez Gene: 3606
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7955)
Rat: Il18, ISOFORM BETA OF INTERLEUKIN-18 PRECURSOR.
Mouse: Il18, INTERLEUKIN-18 PRECURSOR.
Rat: Il18, ISOFORM ALPHA OF INTERLEUKIN-18 PRECURSOR.
Human: IL18, INTERLEUKIN-18 PRECURSOR.
Human: IL18, INTERLEUKIN-18.

Annotations for IL18 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCIEA IEA 
extracellular regionCTAS IEA IEA ISS 
signal transducer activityFTAS ISS 
cytokine activityFIEA 
interleukin-1 receptor bindingFIEA IEA 
interleukin-18 receptor bindingFTAS 
induction of apoptosis via death domain receptorsPTAS 
granulocyte macrophage colony-stimulating factor biosynthetic processPTAS ISS 
response to hypoxiaPIMP 
interleukin-2 biosynthetic processPTAS ISS 
immune responsePTAS IEA TAS ISS ISS 
T-helper 1 type immune responsePIDA ISS 
interleukin-13 biosynthetic processPTAS TAS ISS 
interferon-gamma biosynthetic processPTAS IMP ISS 
sleepPISS ISS TAS 
positive regulation of activated T cell proliferationPIDA IDA ISS ISS 
cell-cell signalingPTAS ISS 
learning and/or memoryPTAS 
angiogenesisPIDA ISS ISS 
regulation of cell adhesionPIDA ISS ISS 
T-helper 2 type immune responsePTAS ISS 
chemokine biosynthetic processPTAS ISS 
response to coldPIEP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (1)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMPUn

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
PneumoniaDIEP
EnterocolitisDIEP

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway