IpiRecord: IPI00290621

IPI00290621 - CD86, ISOFORM 1 OF T-LYMPHOCYTE ACTIVATION ANTIGEN CD86 PRECURSOR.
Uniprot Accession: P42081-1
Uniprot ID: CD86_HUMAN
Mapping: Chr 3, 123256911 - 123322672
Entrez Gene: 942
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10558)
Rat: Cd86, MEMBRANE GLYCOPROTEIN PRECURSOR.
Mouse: Cd86, B7-2 PROTEIN.
Mouse: Cd86, ISOFORM 1 OF T-LYMPHOCYTE ACTIVATION ANTIGEN CD86 PRECURSOR.
Mouse: Cd86, ISOFORM 2 OF T-LYMPHOCYTE ACTIVATION ANTIGEN CD86 PRECURSOR.
Human: CD86, ISOFORM 1 OF T-LYMPHOCYTE ACTIVATION ANTIGEN CD86 PRECURSOR.
Human: CD86, ISOFORM 3 OF T-LYMPHOCYTE ACTIVATION ANTIGEN CD86 PRECURSOR.
Human: CD86, ISOFORM 2 OF T-LYMPHOCYTE ACTIVATION ANTIGEN CD86 PRECURSOR.
Human: CD86, 7 KDA PROTEIN.

Annotations for CD86 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to membraneCRCA ISS 
membraneCIEA 
external side of plasma membraneCIDA IDA IDA ISS 
receptor activityFIEA 
T cell proliferationPIDA 
defense responsePIEA 
T cell activationPIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (8)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
behavior/neurological phenotypeMPUn
immune system phenotypeMPUn
muscle phenotypeMPUn
nervous system phenotypeMPUn
digestive/alimentary phenotypeMPUn
hematopoietic system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cell adhesion molecules (CAMs) (04514)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Type I diabetes mellitus (04940)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway