| IPI00291005 - MDH1, MALATE DEHYDROGENASE, CYTOPLASMIC. | |
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| Uniprot Accession: P40925 | |
| Uniprot ID: MDHC_HUMAN | |
| Mapping: Chr 2, 63669626 - 63687832 | |
| Entrez Gene: 4190 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12093) |
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| Rat: Mdh1, MALATE DEHYDROGENASE, CYTOPLASMIC. |
| Mouse: Mdh1, MALATE DEHYDROGENASE, CYTOPLASMIC. |
| Mouse: Mdh1, MALATE DEHYDROGENASE, SOLUBLE. |
| Human: MDH1, MALATE DEHYDROGENASE, CYTOPLASMIC. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytosol | C | TAS | ISS | ISS |
| cytoplasm | C | IEA | IEA | |
| soluble fraction | C | IDA | ||
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | F | IEA | ||
| malic enzyme activity | F | TAS | ISS | |
| NAD binding | F | IDA | ||
| malate dehydrogenase activity | F | IEA | IDA | |
| L-lactate dehydrogenase activity | F | IEA | ||
| L-malate dehydrogenase activity | F | IEA | IEA IEA | IDA IEA |
| oxidoreductase activity | F | IEA | IEA IEA | IEA |
| tricarboxylic acid cycle intermediate metabolic process | P | IEA | ||
| cellular carbohydrate metabolic process | P | IEA | ||
| malate metabolic process | P | IEA | IEA | IDA IEA |
| oxaloacetate metabolic process | P | IDA | ||
| tricarboxylic acid cycle | P | IEA | IEA | IEA |
| glycolysis | P | IEA | IEA | IEA |
| NAD metabolic process | P | IDA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| citrate cycle pathway | W | IEA | ||
| reductive carboxylate cycle - CO2 fixation pathway | W | IEA | ||
| pyruvate metabolic pathway | W | IEA | ||
| carbon fixation pathway | W | IEA | ||
| glyoxylate and dicarboxylate metabolic pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Citrate cycle (TCA cycle) (00020) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Carbon fixation (00710) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Glyoxylate and dicarboxylate metabolism (00630) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Reductive carboxylate cycle (CO2 fixation) (00720) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pyruvate metabolism (00620) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |