IpiRecord: IPI00291006

IPI00291006 - MDH2, MALATE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR.
Uniprot Accession: Q75MT9
Uniprot ID: Q75MT9_HUMAN
Mapping: Chr 7, 75515328 - 75533863
Entrez Gene: 4191
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10938)
Rat: Mdh2, MALATE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR.
Mouse: Mdh2, MALATE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR.
Human: MDH2, MALATE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR.

Annotations for MDH2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
mitochondrionCIEA IDA ISS ISS ISS IDA IEA 
mitochondrial inner membraneCIDA ISS 
mitochondrial matrixCNAS ISS IDA 
malate dehydrogenase activityFISS ISS IDA 
L-lactate dehydrogenase activityFIEA 
protein bindingFISS IPI 
L-malate dehydrogenase activityFNAS IDA ISS ISS IEA 
malate dehydrogenase (NADP+) activityFIDA 
protein self-associationFIDA 
oxidoreductase activityFIEA IEA IEA 
malate metabolic processPIEA IEA 
tricarboxylic acid cyclePIEA IEA IEA 
glycolysisPIEA IEA 
biological_processPND 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Myocardial InfarctionDIED
Brain IschemiaDIED
Heart Failure, CongestiveDIED

Pathway (5)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
citrate cycle pathwayWIEA
reductive carboxylate cycle - CO2 fixation pathwayWIEA
pyruvate metabolic pathwayWIEA
carbon fixation pathwayWIEA
glyoxylate and dicarboxylate metabolic pathwayWIEA

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Citrate cycle (TCA cycle) (00020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Carbon fixation (00710)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Glyoxylate and dicarboxylate metabolism (00630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Reductive carboxylate cycle (CO2 fixation) (00720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pyruvate metabolism (00620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway