IpiRecord: IPI00292709

IPI00292709 - PCK1, PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC.
Uniprot Accession: P35558
Uniprot ID: PPCKC_HUMAN
Mapping: Chr 20, 55569543 - 55574922
Entrez Gene: 5105
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4091)
Rat: Pck1, PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC.
Mouse: Pck1, PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC.
Human: PCK1, PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC.

Annotations for PCK1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytosolCNR 
soluble fractionCIDA 
cytoplasmCIEA IEA 
lyase activityFIEA IEA IEA 
purine nucleotide bindingFIEA IEA IEA 
phosphoenolpyruvate carboxykinase (GTP) activityFTAS IEA IEA IDA 
carboxy-lyase activityFIEA 
phosphoenolpyruvate carboxykinase activityFIMP IDA ISS 
GTP bindingFIEA IEA IEA IEA 
GDP bindingFIDA 
kinase activityFIEA 
nucleotide bindingFIEA 
lipid metabolic processPIEA IMP ISS IEA 
gluconeogenesisPIEA IDA TAS ISS IEA 
oxaloacetate metabolic processPIDA 
glycerol biosynthetic process from pyruvatePIEA IMP ISS IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
behavior/neurological phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
lethality-postnatalMPUn
normal phenotypeMPUn
growth/size phenotypeMPUn
liver/biliary system phenotypeMPUn

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Diabetes Mellitus, Non-Insulin-DependentDISSISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
glycolysis/gluconeogenesis pathwayWIDA
pyruvate metabolic pathwayWIEA

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
PPAR signaling pathway (03320)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adipocytokine signaling pathway (04920)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Citrate cycle (TCA cycle) (00020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pyruvate metabolism (00620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway