IpiRecord: IPI00293975

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
mitochondrion	C	IEA	IDA IDA	ISS
cytosol	C			TAS
cytoplasm	C	IEA	IEA
nucleus	C			IDA
soluble fraction	C			IDA IDA
peroxidase activity	F		IEA
selenium binding	F	IEA	IEA	IEA TAS IMP
glutathione binding	F			IDA
oxidoreductase activity	F	IEA	IEA	IEA
phospholipid-hydroperoxide glutathione peroxidase activity	F			IMP
glutathione peroxidase activity	F	TAS IEA	IDA IDA IMP	IEA IDA ISS ISS IDA
glutathione metabolic process	P			IDA
induction of apoptosis by oxidative stress	P	IEA	IMP	ISS
response to oxidative stress	P	IEA	IEA	IEA TAS
hydrogen peroxide catabolic process	P	IEA	IMP	IDA
response to reactive oxygen species	P	IEA	IMP	ISS
response to lipid hydroperoxide	P			IMP

Cellular Component

Biological Process

Molecular Function

Phenotype (13)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un Un Un
endocrine/exocrine gland phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un Un Un Un
immune system phenotype	MP		Un Un
nervous system phenotype	MP		Un Un
digestive/alimentary phenotype	MP		Un
no phenotypic analysis	MP		Un
hematopoietic system phenotype	MP		Un
hearing/vestibular/ear phenotype	MP		Un
growth/size phenotype	MP		Un Un
life span-post-weaning/aging	MP		Un Un
brain inflammation	N			ISS
abnormal apoptosis	N			ISS

Disease (6)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Hypercholesterolemia	D			ISS
Diabetic Angiopathies	D			ISS
Myocardial Infarction	D			ISSISS
Hemolysis	D			ISS
Coronary Arteriosclerosis	D			ISSISS
Hypertension	D			ISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
amyotrophic lateral sclerosis disease pathway	W			IEA
glutathione metabolic pathway	W			IEA

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Amyotrophic lateral sclerosis (ALS) (05030)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Arachidonic acid metabolism (00590)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Glutathione metabolism (00480)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway