IPI report for IPI00294395

IpiRecord: IPI00294395

IPI00294395 - C8B, COMPLEMENT COMPONENT C8 BETA CHAIN PRECURSOR.
Uniprot Accession: Q05CV3
Uniprot ID: Q05CV3_HUMAN
Mapping: Chr 1, 57167360 - 57204276
Entrez Gene: 732
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: P07358 UniProtKB/Swiss-Prot: CO8B_HUMAN Vega: OTTHUMP00000010015 REFSEQ_REVIEWED: NP_000057 REFSEQ_REVIEWED: GI:4557391 UniProtKB/TrEMBL: A1L4K7 UniProtKB/TrEMBL: A1L4K7_HUMAN UniProtKB/TrEMBL: Q05CV3 UniProtKB/TrEMBL: Q05CV3_HUMAN ENSEMBL: ENSP00000360281 ENSEMBL: ENSG00000021852 H-InvDB: HIT000194504 UniParc: UPI0000127C5C HGNC: 1353 Entrez Gene: 732 UniGene: Hs.391835 CCDS: CCDS30730.1 trome: HTR009567 UTRdb: BB001838 UTRdb: BB003648 UTRdb: BB312954 RZPD: Hs.391835 CleanEx: HS_C8B InterPro: IPR002172 InterPro: IPR001862 InterPro: IPR000884 Pfam: PF00057 Pfam: PF01823 Pfam: PF00090 PRINTS: PR00764 SMART: SM00192 SMART: SM00457 SMART: SM00209 PROSITE: PS01209 PROSITE: PS50068 PROSITE: PS00279 PROSITE: PS50092

IPI00294395 - C8B, COMPLEMENT COMPONENT C8 BETA CHAIN PRECURSOR.

Uniprot Accession: Q05CV3

Uniprot ID: Q05CV3_HUMAN

Mapping: Chr 1, 57167360 - 57204276

Entrez Gene: 732

Entrez MapView: Geneprod

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5545)
Rat: C8b, COMPLEMENT COMPONENT C8 BETA CHAIN PRECURSOR.
Mouse: C8b, ISOFORM 1 OF COMPLEMENT COMPONENT C8 BETA CHAIN PRECURSOR.
Mouse: C8b, ISOFORM 2 OF COMPLEMENT COMPONENT C8 BETA CHAIN PRECURSOR.
Rat: C8b, 59 KDA PROTEIN.
Human: C8B, COMPLEMENT COMPONENT C8 BETA CHAIN PRECURSOR.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5545)

Rat: C8b, COMPLEMENT COMPONENT C8 BETA CHAIN PRECURSOR.

Mouse: C8b, ISOFORM 1 OF COMPLEMENT COMPONENT C8 BETA CHAIN PRECURSOR.

Mouse: C8b, ISOFORM 2 OF COMPLEMENT COMPONENT C8 BETA CHAIN PRECURSOR.

Rat: C8b, 59 KDA PROTEIN.

Human: C8B, COMPLEMENT COMPONENT C8 BETA CHAIN PRECURSOR.

Annotations for C8B and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular space	C	NR		IDA
membrane	C	TAS
membrane attack complex	C	IEA	RCA	IEA ISS
protein complex binding	F			IDA
immune response	P		IEA
complement activation, classical pathway	P	IEA	RCA	IEA ISS
complement activation	P		IEA
complement activation, alternative pathway	P	IEA	RCA	IEA ISS
cytolysis	P	IEA	RCA	IEA ISS IDA
innate immune response	P		IEA

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Myocardial Infarction	D			IEP

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Complement and coagulation cascades (04610)	Present in KEGG pathway	Present in KEGG pathway	Not present in KEGG pathway