IpiRecord: IPI00294501

IPI00294501 - DHCR7, 7-DEHYDROCHOLESTEROL REDUCTASE.
Uniprot Accession: Q9UBM7
Uniprot ID: DHCR7_HUMAN
Mapping: Chr 11, 70823111 - 70837050
Entrez Gene: 1717
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1346)
Rat: Dhcr7, 7-DEHYDROCHOLESTEROL REDUCTASE.
Mouse: Dhcr7, 7-DEHYDROCHOLESTEROL REDUCTASE.
Mouse: Dhcr7, 24 KDA PROTEIN.
Mouse: Dhcr7, 26 KDA PROTEIN.
Human: DHCR7, 7-DEHYDROCHOLESTEROL REDUCTASE.

Annotations for DHCR7 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nuclear outer membraneCIDA ISS ISS IEA 
endoplasmic reticulumCIDA IEA ISS ISS IEA 
membraneCIEA IEA IEA IEA 
integral to nuclear inner membraneCISS 
integral to membraneCIEA RCA ISS IEA 
oxidoreductase activityFIEA IEA IEA 
protein bindingFIPI 
7-dehydrocholesterol reductase activityFIDA IDA TAS ISS ISS IEA 
sterol biosynthetic processPIMP ISS 
regulation of cholesterol biosynthetic processPIDA 
blood vessel developmentPIEA IMP ISS IEA 
lung developmentPIEA IMP ISS IEA 
cell differentiationPIEA IMP ISS IEA 
lipid biosynthetic processPIEA 
cholesterol biosynthetic processPIMP IEA TAS IDA ISS IEA 
regulation of cell proliferationPIEA IMP ISS IEA 
steroid biosynthetic processPIEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (14)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
craniofacial phenotypeMP##
behavior/neurological phenotypeMP##
homeostasis/metabolism phenotypeMP###
limbs/digits/tail phenotypeMP##
lethality-embryonic/perinatalMP###
digestive/alimentary phenotypeMP##
renal/urinary system phenotypeMP##
respiratory system phenotypeMP##
nervous system phenotypeMP##
growth/size phenotypeMP##
abnormal stationary movementNISS
postnatal growth retardationNISS
abnormal eating behaviorNISS
abnormal craniofacial morphologyNISS

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Smith-Lemli-Opitz SyndromeDISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
steroid biosynthetic pathwayWIEA

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Biosynthesis of steroids (00100)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway