| IPI00295004 - ALS2, ISOFORM 1 OF ALSIN. | |
|---|---|
| Uniprot Accession: Q6IQ41 | |
| Uniprot ID: Q6IQ41_HUMAN | |
| Mapping: Chr 2, 202273522 - 202353983 | |
| Entrez Gene: 57679 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_15559) |
|---|
| Human: ALS2, ISOFORM 2 OF ALSIN. |
| Mouse: Als2, ISOFORM 2 OF ALSIN. |
| Mouse: Als2, ISOFORM 1 OF ALSIN. |
| Mouse: Als2, FULL INSERT SEQUENCE. |
| Mouse: Als2, 72 KDA PROTEIN. |
| Mouse: Als2, 55 KDA PROTEIN. |
| Human: ALS2, ISOFORM 1 OF ALSIN. |
| Human: ALS2, ISOFORM 3 OF ALSIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | IDA | ||
| nucleus | C | ISS | ||
| centrosome | C | IDA ISS | ||
| cytosol | C | ISS | ||
| dendritic spine | C | IDA | ||
| postsynaptic density | C | IDA | ||
| early endosome | C | ISS | ||
| intracellular | C | IEA | ||
| guanyl-nucleotide exchange factor activity | F | IEA IEA | ||
| Rab GTPase binding | F | ISS | ||
| protein binding | F | IPI ISS | ||
| Rab GTPase activator activity | F | ISS | ||
| Rac GTPase activator activity | F | ISS | ||
| Rac GTPase binding | F | ISS | ||
| identical protein binding | F | ISS | ||
| Rho guanyl-nucleotide exchange factor activity | F | IEA | ||
| vesicle organization and biogenesis | P | IDA | ||
| response to oxidative stress | P | IMP | ||
| behavioral fear response | P | IMP | ||
| receptor recycling | P | IMP | ||
| intracellular signaling cascade | P | IEA | ||
| endosome organization and biogenesis | P | ISS | ||
| protein localization | P | IMP | ||
| regulation of Rho protein signal transduction | P | IEA | ||
| synaptic transmission, glutamatergic | P | IMP | ||
| locomotory behavior | P | IMP IMP | ||
| neuromuscular junction development | P | IMP | ||
| regulation of Rab GTPase activity | P | IDA | ||
| protein homooligomerization | P | ISS | ||
| lysosomal transport | P | ISS | ||
| endosome transport | P | IMP IMP |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| behavior/neurological phenotype | MP | Un Un Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| muscle phenotype | MP | Un | ||
| nervous system phenotype | MP | Un Un Un | ||
| growth/size phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Amyotrophic lateral sclerosis (ALS) (05030) | Present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Neurodegenerative Disorders (01510) | Present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |