IpiRecord: IPI00296053

IPI00296053 - FH, ISOFORM MITOCHONDRIAL OF FUMARATE HYDRATASE, MITOCHONDRIAL PRECURSOR.
Uniprot Accession: Q5SY06
Uniprot ID: Q5SY06_HUMAN
Mapping: Chr 1, 239727526 - 239749684
Entrez Gene: 2271
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11554)
Rat: Fh1, ISOFORM MITOCHONDRIAL OF FUMARATE HYDRATASE, MITOCHONDRIAL PRECURSOR.
Mouse: Fh1, ISOFORM MITOCHONDRIAL OF FUMARATE HYDRATASE, MITOCHONDRIAL PRECURSOR.
Mouse: Fh1, ISOFORM CYTOPLASMIC OF FUMARATE HYDRATASE, MITOCHONDRIAL PRECURSOR.
Rat: Fh1, ISOFORM CYTOPLASMIC OF FUMARATE HYDRATASE, MITOCHONDRIAL PRECURSOR.
Human: FH, ISOFORM MITOCHONDRIAL OF FUMARATE HYDRATASE, MITOCHONDRIAL PRECURSOR.
Human: FH, ISOFORM CYTOPLASMIC OF FUMARATE HYDRATASE, MITOCHONDRIAL PRECURSOR.

Annotations for FH and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytosolCISS 
tricarboxylic acid cycle enzyme complexCIEA 
mitochondrionCIDA ISS ISS ISS 
cytoplasmCIEA ISS 
lyase activityFIEA 
catalytic activityFIEA 
fumarate hydratase activityFIEA IEA IMP ISS 
homeostasis of number of cells within a tissuePIMP 
tricarboxylic acid cyclePIEA 
fumarate metabolic processPIEA ISS TAS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (3)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMP#
lethality-embryonic/perinatalMP#
renal/urinary system phenotypeMP#

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Kidney NeoplasmsDISS
LeiomyomatosisDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Citrate cycle (TCA cycle) (00020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Reductive carboxylate cycle (CO2 fixation) (00720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway