IpiRecord: IPI00297261

IPI00297261 - PTPN1, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1.
Uniprot Accession: P18031
Uniprot ID: PTN1_HUMAN
Mapping: Chr 20, 48560294 - 48634706
Entrez Gene: 5770
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4101)
Rat: Ptpn1, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1.
Mouse: Ptpn1, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1.
Human: PTPN1, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1.
Human: PTPN1, PROTEIN TYROSINE PHOSPHATASE 1B (FRAGMENT).

Annotations for PTPN1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to membraneCRCA ISS 
membraneCIEA IEA 
soluble fractionCNR 
anchored to membraneCNAS 
endoplasmic reticulumCIEA IEA IEA 
cytoplasmCNR 
hydrolase activityFIEA IEA IEA 
receptor activityFIEA 
protein bindingFIPI IPI IPI IPI 
protein tyrosine phosphatase activityFTAS IEA IEA IEA ISS IEA 
phosphoric monoester hydrolase activityFIEA 
insulin receptor bindingFIMP 
phosphoprotein phosphatase activityFIEA 
protein amino acid dephosphorylationPIEA IMP ISS ISS IEA 
dephosphorylationPIEA 
regulation of insulin receptor signaling pathwayPIMP 
insulin receptor signaling pathwayPIEA IMP ISS IEA 
signal transductionPTAS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (11)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
adipose tissue phenotypeMPUn Un
skin/coat/nails phenotypeMPUn
behavior/neurological phenotypeMPUn Un
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn Un Un
immune system phenotypeMPUn
skeleton phenotypeMPUn
digestive/alimentary phenotypeMPUn
hematopoietic system phenotypeMPUn
growth/size phenotypeMPUn Un
life span-post-weaning/agingMPUn

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Insulin ResistanceDISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
insulin signaling pathwayWIMPISS

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway