| IPI00297261 - PTPN1, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1. | |
|---|---|
| Uniprot Accession: P18031 | |
| Uniprot ID: PTN1_HUMAN | |
| Mapping: Chr 20, 48560294 - 48634706 | |
| Entrez Gene: 5770 | |
| Entrez MapView: |
|
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4101) |
|---|
| Rat: Ptpn1, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1. |
| Mouse: Ptpn1, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1. |
| Human: PTPN1, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1. |
| Human: PTPN1, PROTEIN TYROSINE PHOSPHATASE 1B (FRAGMENT). |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integral to membrane | C | RCA | ISS | |
| membrane | C | IEA | IEA | |
| soluble fraction | C | NR | ||
| anchored to membrane | C | NAS | ||
| endoplasmic reticulum | C | IEA | IEA | IEA |
| cytoplasm | C | NR | ||
| hydrolase activity | F | IEA | IEA | IEA |
| receptor activity | F | IEA | ||
| protein binding | F | IPI IPI IPI | IPI | |
| protein tyrosine phosphatase activity | F | TAS | IEA IEA IEA | ISS IEA |
| phosphoric monoester hydrolase activity | F | IEA | ||
| insulin receptor binding | F | IMP | ||
| phosphoprotein phosphatase activity | F | IEA | ||
| protein amino acid dephosphorylation | P | IEA | IMP | ISS ISS IEA |
| dephosphorylation | P | IEA | ||
| regulation of insulin receptor signaling pathway | P | IMP | ||
| insulin receptor signaling pathway | P | IEA | IMP | ISS IEA |
| signal transduction | P | TAS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| adipose tissue phenotype | MP | Un Un | ||
| skin/coat/nails phenotype | MP | Un | ||
| behavior/neurological phenotype | MP | Un Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un Un | ||
| immune system phenotype | MP | Un | ||
| skeleton phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| hematopoietic system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un Un | ||
| life span-post-weaning/aging | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Insulin Resistance | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| insulin signaling pathway | W | IMPISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Adherens junction (04520) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Insulin signaling pathway (04910) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |