IpiRecord: IPI00298267

IPI00298267 - PTGS1, CYCLOOXYGENASE 1B3.
Uniprot Accession: Q5T7T7
Uniprot ID: Q5T7T7_HUMAN
Mapping: Chr 9, 124173050 - 124197802
Entrez Gene: 5742
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3170)
Rat: Ptgs1, PROSTAGLANDIN G/H SYNTHASE 1 PRECURSOR.
Mouse: Ptgs1, PROSTAGLANDIN G/H SYNTHASE 1 PRECURSOR.
Mouse: Ptgs1, PUTATIVE CYCLOOXYGENASE 3.
Rat: Ptgs1, PTGS1 PROTEIN.
Human: PTGS1, CYCLOOXYGENASE 1B3.
Human: PTGS1, ISOFORM SHORT OF PROSTAGLANDIN G/H SYNTHASE 1 PRECURSOR.
Human: PTGS1, PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 1.
Human: PTGS1, PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 1 ISOFORM 2 PRECURSOR.
Human: PTGS1, CYCLOOXYGENASE 1B1.

Annotations for PTGS1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCRCA ISS 
cytoplasmCIDA ISS ISS 
endoplasmic reticulumCIEA 
microsomeCIDA ISS ISS 
nucleusCIDA ISS 
membraneCIEA IEA 
iron ion bindingFIEA IEA 
lipid bindingFIMP 
heme bindingFIEA IEA 
peroxidase activityFIEA IEA IEA IEA 
oxidoreductase activityFIEA IEA 
prostaglandin-endoperoxide synthase activityFIEA TAS ISS IEA 
metal ion bindingFIEA IEA 
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygenFIEA IEA 
lipid metabolic processPISS 
response to oxidative stressPIEA IEA 
keratinocyte differentiationPNAS 
lipid biosynthetic processPIEA 
fatty acid biosynthetic processPIEA IEA 
blood pressure regulationPIMP ISS ISS 
prostaglandin biosynthetic processPIMP TAS ISS IEA ISS 
electron transportPIEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (10)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn Un
immune system phenotypeMPUn Un
lethality-embryonic/perinatalMPUn Un
renal/urinary system phenotypeMPUn Un
digestive/alimentary phenotypeMPUn
cardiovascular system phenotypeMPUn Un
hematopoietic system phenotypeMPUn Un
reproductive system phenotypeMPUn Un
life span-post-weaning/agingMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
eicosanoids metabolic pathwayWIEA

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Arachidonic acid metabolism (00590)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway