| IPI00298306 - ATM, SERINE-PROTEIN KINASE ATM. | |
|---|---|
| Uniprot Accession: Q6P7P1 | |
| Uniprot ID: Q6P7P1_HUMAN | |
| Mapping: Chr 11, 107598769 - 107745036 | |
| Entrez Gene: 472 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7989) |
|---|
| Rat: IPI00369732, SIMILAR TO SERINE-PROTEIN KINASE ATM. |
| Mouse: Atm, SERINE-PROTEIN KINASE ATM. |
| Human: ATM, ATAXIA TELANGIECTASIA MUTATED PROTEIN ISOFORM 2. |
| Human: ATM, SERINE-PROTEIN KINASE ATM. |
| Human: ATM, 351 KDA PROTEIN. |
| Human: ATM, ATAXIA TELANGIECTASIA MUTATED. |
| Human: ATM, ATM (FRAGMENT). |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| intracellular | C | RCA | ||
| nucleus | C | IEA | TAS | |
| cytoplasmic vesicle | C | IEA | IEA | |
| spindle | C | IDA | ||
| 1-phosphatidylinositol-3-kinase activity | F | IMP | ||
| phosphotransferase activity, alcohol group as acceptor | F | IEA | IEA | |
| kinase activity | F | IEA | ||
| protein serine/threonine kinase activity | F | IDA | TAS | |
| DNA binding | F | IEA | IEA | |
| transcription factor activity | F | RCA | ||
| protein kinase activity | F | TAS IDA | ||
| protein N-terminus binding | F | IDA | ||
| transferase activity | F | IEA | IEA | |
| signal transduction | P | TAS | ||
| negative regulation of progression through cell cycle | P | IEA | IEA | |
| DNA damage response, signal transduction resulting in induction of apoptosis | P | IMP IGI | ||
| protein amino acid phosphorylation | P | IDA | ||
| cell cycle | P | IEA | IEA | |
| DNA repair | P | TAS | IDA IMP IMP | |
| mitotic cell cycle spindle assembly checkpoint | P | IMP | ||
| female gamete generation | P | IMP | ||
| response to ionizing radiation | P | IDA | ||
| heart development | P | IGI | ||
| meiotic recombination | P | TAS | ||
| DNA damage checkpoint | P | IMP | ||
| response to DNA damage stimulus | P | TAS | ||
| regulation of transcription, DNA-dependent | P | RCA | ||
| somitogenesis | P | IGI | ||
| brain development | P | IGI |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un Un Un Un Un Un | ||
| behavior/neurological phenotype | MP | Un Un Un | ||
| endocrine/exocrine gland phenotype | MP | Un Un Un Un | ||
| immune system phenotype | MP | Un Un Un Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un | ||
| nervous system phenotype | MP | Un Un Un Un Un Un | ||
| tumorigenesis | MP | Un Un Un Un Un Un | ||
| hematopoietic system phenotype | MP | Un Un Un Un Un | ||
| reproductive system phenotype | MP | Un Un Un Un Un Un | ||
| growth/size phenotype | MP | Un Un Un Un Un Un | ||
| life span-post-weaning/aging | MP | Un Un Un Un Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Cell cycle (04110) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Apoptosis (04210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |