| IPI00298347 - PTPN11, ISOFORM 2 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11. | |
|---|---|
| Uniprot Accession: Q06124-2 | |
| Uniprot ID: PTN11_HUMAN | |
| Mapping: Chr 12, 111340919 - 111432099 | |
| Entrez Gene: 5781 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11103) |
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| Rat: Ptpn11, ISOFORM 2 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11. |
| Mouse: Ptpn11, PTPN11 PROTEIN. |
| Mouse: Ptpn11, ISOFORM 1 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11. |
| Mouse: Ptpn11, ISOFORM 2 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11. |
| Rat: Ptpn11, ISOFORM 1 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11. |
| Human: PTPN11, PTPN11 PROTEIN. |
| Human: PTPN11, ISOFORM 2 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11. |
| Human: PTPN11, ISOFORM 3 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11. |
| Human: PTPN11, ISOFORM 1 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| stress fiber | C | ISS | ||
| cell junction | C | ISS | ||
| cytoplasm | C | IEA | ||
| soluble fraction | C | IDA | ||
| membrane fraction | C | ISS | ||
| mitochondrion | C | IDA | ||
| non-membrane spanning protein tyrosine phosphatase activity | F | RCA | ISS ISS | |
| hydrolase activity | F | IEA | ||
| protein binding | F | IPI | IPI ISS IPI IPI IPI IPI | ISS ISS ISS IDA IDA |
| phosphoric monoester hydrolase activity | F | IEA | ||
| receptor activity | F | IEA | ||
| phosphoprotein phosphatase activity | F | IMP | ISS | |
| phospholipase binding | F | IDA | ||
| protein tyrosine phosphatase activity | F | IEA IEA IEA | IDA IDA IDA | |
| intracellular signaling cascade | P | IEA | ||
| axonogenesis | P | IMP | ISS | |
| activation of MAPK activity | P | IMP IMP | ISS | |
| protein amino acid dephosphorylation | P | IEA | IDA | |
| regulation of protein export from nucleus | P | IMP | ISS | |
| nerve growth factor receptor signaling pathway | P | IMP | ISS | |
| dephosphorylation | P | IEA | ||
| signal transduction | P | RCA | ISS | |
| DNA damage checkpoint | P | IMP | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| adipose tissue phenotype | MP | Un Un | ||
| cellular phenotype | MP | Un Un | ||
| craniofacial phenotype | MP | Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un | ||
| embryogenesis phenotype | MP | Un Un | ||
| immune system phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un Un Un Un | ||
| lethality-postnatal | MP | Un | ||
| skeleton phenotype | MP | Un | ||
| muscle phenotype | MP | Un Un Un | ||
| nervous system phenotype | MP | Un | ||
| respiratory system phenotype | MP | Un | ||
| vision/eye phenotype | MP | Un Un | ||
| normal phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un Un Un | ||
| reproductive system phenotype | MP | Un Un | ||
| hematopoietic system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un Un Un | ||
| liver/biliary system phenotype | MP | Un Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Craniofacial Abnormalities | D | ISS | ||
| Heart Defects, Congenital | D | ISS | ||
| Noonan Syndrome | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| somatostatin signaling pathway | W | IDA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Epithelial cell signaling in Helicobacter pylori infection (05120) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Chronic myeloid leukemia (05220) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Adipocytokine signaling pathway (04920) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Jak-STAT signaling pathway (04630) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Leukocyte transendothelial migration (04670) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Natural killer cell mediated cytotoxicity (04650) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |