IpiRecord: IPI00298887

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
nucleus	C	IEA	IDA IDA	IEA ISS ISS
cytoplasm	C		IDA IDA IDA	ISS ISS
plasma membrane	C		IDA	ISS
transcription factor binding	F			ISS
signal transducer activity	F	IEA	IEA	IEA
transcription factor activity	F	IEA	IEA	IEA TAS ISS
hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity	F			ISS
protein binding	F		IPI IPI	ISS
transcription activator activity	F		IDA	ISS
DNA binding	F		IDA IDA	IDA ISS
protein dimerization activity	F		IPI	ISS
calcium ion binding	F	IEA	IEA	IEA
signal transduction	P	IEA	IEA
regulation of body size	P		IMP	ISS
cell motility	P			ISS
intracellular signaling cascade	P	IEA	IEA	IEA
thermoregulation	P		IMP	ISS
sexual reproduction	P		IMP	ISS
nervous system development	P			ISS
eating behavior	P		IMP	ISS
cytokine and chemokine mediated signaling pathway	P		NAS	ISS
acute-phase response	P		IEA	IEP ISS
transcription from RNA polymerase II promoter	P		IDA	ISS
JAK-STAT cascade	P		TAS	TAS ISS ISS
transcription	P		IEA	IEA
eye photoreceptor cell differentiation	P		IMP	ISS
glucose homeostasis	P		IMP	ISS
regulation of transcription, DNA-dependent	P	IEA	IEA IEA	IEA
regulation of transcription from RNA polymerase II promoter	P		IDA	ISS
negative regulation of transcription from RNA polymerase II promoter	P			ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (10)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un Un
homeostasis/metabolism phenotype	MP		Un
immune system phenotype	MP		Un Un Un Un Un Un Un
embryogenesis phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un Un
lethality-postnatal	MP		Un Un
vision/eye phenotype	MP		Un
normal phenotype	MP		Un Un
hematopoietic system phenotype	MP		Un Un
growth/size phenotype	MP		Un Un Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
leptin system pathway	W			ISSISS
JAK-STAT signaling pathway	W			TASISS

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Adipocytokine signaling pathway (04920)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Pancreatic cancer (05212)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway