| IPI00299402 - PC, PYRUVATE CARBOXYLASE, MITOCHONDRIAL PRECURSOR. | |
|---|---|
| Uniprot Accession: P11498 | |
| Uniprot ID: PYC_HUMAN | |
| Mapping: Chr 11, 66372605 - 66396206 | |
| Entrez Gene: 5091 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1497) |
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| Rat: Pc, PYRUVATE CARBOXYLASE, MITOCHONDRIAL PRECURSOR. |
| Mouse: Pcx, CLONE:F830201B12 PRODUCT:PYRUVATE CARBOXYLASE, FULL INSERT SEQUENCE. |
| Human: PC, PYRUVATE CARBOXYLASE, MITOCHONDRIAL PRECURSOR. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | IEA | IEA | IEA |
| soluble fraction | C | IDA | ||
| mitochondrion | C | IEA | IDA | IEA ISS |
| mitochondrial inner membrane | C | IEA | IDA | IEA ISS |
| ligase activity | F | IEA | IEA IEA | IEA |
| manganese ion binding | F | IEA | IEA | IEA |
| pyruvate carboxylase activity | F | TAS | IEA IEA | IEA ISS ISS IMP IDA |
| catalytic activity | F | IEA IEA | ||
| carboxylic acid binding | F | IDA | ||
| ATP binding | F | TAS | IEA IEA | IEA ISS ISS IDA |
| biotin binding | F | TAS | IEA | IEA ISS ISS IMP |
| nucleotide binding | F | IEA | IEA | IEA |
| lipid biosynthetic process | P | IEA | IEA | IEA |
| gluconeogenesis | P | IEA | IEA IEA | IEA |
| oxaloacetate metabolic process | P | IDA | ||
| pyruvate metabolic process | P | IDA | ||
| metabolic process | P | IEA | IEA | IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Pyruvate Carboxylase Deficiency Disease | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| citrate cycle pathway | W | IEA | ||
| alanine and aspartate metabolic pathway | W | IEA | ||
| pyruvate metabolic pathway | W | IEA IDA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Citrate cycle (TCA cycle) (00020) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pyruvate metabolism (00620) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Alanine and aspartate metabolism (00252) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |