IpiRecord: IPI00299402

IPI00299402 - PC, PYRUVATE CARBOXYLASE, MITOCHONDRIAL PRECURSOR.
Uniprot Accession: P11498
Uniprot ID: PYC_HUMAN
Mapping: Chr 11, 66372605 - 66396206
Entrez Gene: 5091
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1497)
Rat: Pc, PYRUVATE CARBOXYLASE, MITOCHONDRIAL PRECURSOR.
Mouse: Pcx, CLONE:F830201B12 PRODUCT:PYRUVATE CARBOXYLASE, FULL INSERT SEQUENCE.
Human: PC, PYRUVATE CARBOXYLASE, MITOCHONDRIAL PRECURSOR.

Annotations for PC and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCIEA IEA IEA 
soluble fractionCIDA 
mitochondrionCIEA IDA IEA ISS 
mitochondrial inner membraneCIEA IDA IEA ISS 
ligase activityFIEA IEA IEA IEA 
manganese ion bindingFIEA IEA IEA 
pyruvate carboxylase activityFTAS IEA IEA IEA ISS ISS IMP IDA 
catalytic activityFIEA IEA 
carboxylic acid bindingFIDA 
ATP bindingFTAS IEA IEA IEA ISS ISS IDA 
biotin bindingFTAS IEA IEA ISS ISS IMP 
nucleotide bindingFIEA IEA IEA 
lipid biosynthetic processPIEA IEA IEA 
gluconeogenesisPIEA IEA IEA IEA 
oxaloacetate metabolic processPIDA 
pyruvate metabolic processPIDA 
metabolic processPIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Pyruvate Carboxylase Deficiency DiseaseDISS

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
citrate cycle pathwayWIEA
alanine and aspartate metabolic pathwayWIEA
pyruvate metabolic pathwayWIEA IDA

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Citrate cycle (TCA cycle) (00020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pyruvate metabolism (00620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Alanine and aspartate metabolism (00252)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway