| IPI00300018 - AIFM1, ISOFORM 2 OF APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL PRECURSOR. | |
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| Uniprot Accession: Q5JUZ8 | |
| Uniprot ID: Q5JUZ8_HUMAN | |
| Mapping: Chr X, 129091018 - 129127489 | |
| Entrez Gene: 9131 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14994) |
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| Rat: Pdcd8, APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL PRECURSOR. |
| Mouse: Aifm1, APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL PRECURSOR. |
| Mouse: Aifm1, PROGRAMMED CELL DEATH 8. |
| Rat: Pdcd8, APOPTOSIS-INDUCING FACTOR. |
| Human: AIFM1, ISOFORM 1 OF APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL PRECURSOR. |
| Human: AIFM1, ISOFORM 3 OF APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL PRECURSOR. |
| Human: AIFM1, ISOFORM 2 OF APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL PRECURSOR. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| mitochondrial outer membrane | C | TAS | ISS | |
| soluble fraction | C | IDA | ISS | |
| cytoplasm | C | IEA | IEA | |
| cytosol | C | TAS | ISS | |
| nucleus | C | IDA TAS | IDA ISS ISS IEA | |
| microsome | C | IDA | ISS | |
| mitochondrion | C | IDA IDA IDA | IDA ISS ISS IEA | |
| mitochondrial intermembrane space | C | TAS | ISS | |
| FAD binding | F | IEA | IEA | |
| electron carrier activity | F | ISS | ||
| electron-transferring-flavoprotein dehydrogenase activity | F | TAS | ISS | |
| protein binding | F | ISS | ||
| oxidoreductase activity | F | IEA IEA | IEA | |
| DNA binding | F | IEA | IEA | |
| DNA damage response, signal transduction resulting in induction of apoptosis | P | ISS | ||
| apoptosis | P | IEA | IEA | |
| DNA fragmentation during apoptosis | P | TAS | IPI ISS ISS | |
| apoptotic mitochondrial changes | P | TAS | ISS | |
| apoptotic chromosome condensation | P | IPI | ||
| cell redox homeostasis | P | IEA | IEA | |
| electron transport | P | IEA | IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| cellular phenotype | MP | Un Un | ||
| behavior/neurological phenotype | MP | Un Un | ||
| homeostasis/metabolism phenotype | MP | Un Un | ||
| embryogenesis phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| muscle phenotype | MP | Un Un | ||
| nervous system phenotype | MP | Un Un | ||
| vision/eye phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un Un | ||
| growth/size phenotype | MP | Un Un | ||
| life span-post-weaning/aging | MP | Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Apoptosis (04210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |