| IPI00300050 - HSD11B2, CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 2. | |
|---|---|
| Uniprot Accession: Q9UCW8 | |
| Uniprot ID: Q9UCW8_HUMAN | |
| Mapping: Chr 16, 66022518 - 66028953 | |
| Entrez Gene: 3291 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13912) |
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| Rat: Hsd11b2, CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 2. |
| Mouse: Hsd11b2, CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 2. |
| Human: HSD11B2, CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 2. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| microsome | C | IEA | IEA | IEA IDA |
| extracellular space | C | RCA | ISS | |
| cytoplasm | C | IDA | ||
| endoplasmic reticulum | C | IEA | IEA | IEA |
| NAD binding | F | IDA | ||
| steroid binding | F | IPI | ||
| 11-beta-hydroxysteroid dehydrogenase activity | F | IDA IMP | ||
| oxidoreductase activity | F | IEA | IEA IEA | IDA IEA |
| metabolic process | P | IEA | IEA | IDA IEA |
| cell-cell signaling | P | NR | ISS | |
| aldosterone mediated regulation of body fluids | P | IMP | ||
| glucocorticoid metabolic process | P | IDA | ||
| glucocorticoid biosynthetic process | P | TAS | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| behavior/neurological phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| lethality-postnatal | MP | Un | ||
| muscle phenotype | MP | Un | ||
| renal/urinary system phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| normal phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un | ||
| no phenotypic analysis | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Metabolism, Inborn Errors | D | ISS | ||
| Obesity | D | IEPISS | ||
| Hypertension | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| C21-Steroid hormone metabolic pathway | W | IEA | ||
| androgen and estrogen metabolic pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| C21-Steroid hormone metabolism (00140) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Androgen and estrogen metabolism (00150) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |