IpiRecord: IPI00302552

IPI00302552 - ACVR1C, ISOFORM 1 OF ACTIVIN RECEPTOR TYPE-1C PRECURSOR.
Uniprot Accession: Q8NER5-1
Uniprot ID: ACV1C_HUMAN
Mapping: Chr 2, 158097152 - 158193645
Entrez Gene: 130399
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3252)
Rat: Acvr1c, ACTIVIN RECEPTOR TYPE-1C PRECURSOR.
Mouse: Acvr1c, ACTIVIN A RECEPTOR TYPE IC.
Mouse: Acvr1c, ACTIVIN RECEPTOR TYPE-1C PRECURSOR.
Mouse: Acvr1c, ACTIVIN A RECEPTOR TYPE IC.
Mouse: Acvr1c, ACTIVIN A RECEPTOR TYPE IC.
Rat: Acvr1c, 41 KDA PROTEIN.
Human: ACVR1C, ISOFORM 1 OF ACTIVIN RECEPTOR TYPE-1C PRECURSOR.
Human: ACVR1C, ISOFORM 2 OF ACTIVIN RECEPTOR TYPE-1C PRECURSOR.
Human: ACVR1C, ISOFORM 3 OF ACTIVIN RECEPTOR TYPE-1C PRECURSOR.
Human: ACVR1C, ISOFORM 4 OF ACTIVIN RECEPTOR TYPE-1C PRECURSOR.

Annotations for ACVR1C and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
activin receptor complexCISS IDA 
integral to membraneCIEA IEA 
membraneCIEA IEA IEA 
cell surfaceCISS 
activin receptor activity, type IFISS IDA 
metal ion bindingFIEA 
ATP bindingFIEA IEA ISS IC 
protein serine/threonine kinase activityFIEA IEA IDA 
manganese ion bindingFIEA IEA 
SMAD bindingFIDA 
activin bindingFISS IPI IDA IDA 
transforming growth factor beta receptor activityFIEA IEA 
receptor signaling protein serine/threonine kinase activityFISS 
receptor activityFIEA IEA 
transmembrane receptor protein serine/threonine kinase activityFIEA 
magnesium ion bindingFIEA IEA 
transferase activityFIEA IEA 
kinase activityFIEA 
protein kinase activityFIEA 
nucleotide bindingFIEA IEA 
protein amino acid phosphorylationPIEA ISS IC 
cell differentiationPISS IDA 
in utero embryonic developmentPIMP 
determination of left/right symmetryPIMP 
trophectodermal cell proliferationPISS 
regulation of apoptosisPISS IDA 
positive regulation of apoptosisPISS 
apoptosisPIEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
normal phenotypeMPUn
life span-post-weaning/agingMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (6)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
TGF-beta signaling pathway (04350)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway