IPI report for IPI00303963

IpiRecord: IPI00303963

IPI00303963 - C2, COMPLEMENT C2 PRECURSOR (FRAGMENT).
Uniprot Accession: Q95IG1
Uniprot ID: Q95IG1_HUMAN
Mapping: Chr 6, 32030300 - 32048254
Entrez Gene: 717
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: P06681 UniProtKB/Swiss-Prot: CO2_HUMAN Vega: OTTHUMP00000014614 Vega: OTTHUMP00000029277 Vega: OTTHUMP00000029712 REFSEQ_REVIEWED: NP_000054 REFSEQ_REVIEWED: GI:14550407 UniProtKB/TrEMBL: Q53GZ8 UniProtKB/TrEMBL: Q53GZ8_HUMAN UniProtKB/TrEMBL: Q53HP3 UniProtKB/TrEMBL: Q53HP3_HUMAN UniProtKB/TrEMBL: Q5JP69 UniProtKB/TrEMBL: Q5JP69_HUMAN UniProtKB/TrEMBL: Q95IG1 UniProtKB/TrEMBL: Q95IG1_HUMAN ENSEMBL: ENSP00000299367 ENSEMBL: ENSG00000166278 ENSEMBL: ENSP00000364660 ENSEMBL: ENSG00000204364 ENSEMBL: ENSP00000372853 ENSEMBL: ENSG00000206372 UniParc: UPI000000DA4D HGNC: 1248 Entrez Gene: 717 UniGene: Hs.408903 CCDS: CCDS4728.1 trome: HTR008384 UTRdb: BB006791 UTRdb: BB234777 UTRdb: BB283129 UTRdb: BB323790 UTRdb: BB323791 UTRdb: BB323793 UTRdb: BB379919 UTRdb: BB379921 UTRdb: BB381780 UTRdb: BB381785 UTRdb: BB381786 UTRdb: BB381790 UTRdb: CC265704 UTRdb: CC316773 UTRdb: CC360500 UTRdb: CC360503 UTRdb: CC425032 UTRdb: CC427132 UTRdb: CC427140 RZPD: Hs.408903 CleanEx: HS_C2 InterPro: IPR011360 InterPro: IPR009003 InterPro: IPR001254 InterPro: IPR001314 InterPro: IPR000436 InterPro: IPR002035 Pfam: PF00084 Pfam: PF00089 Pfam: PF00092 PRINTS: PR00722 PRINTS: PR00453 SMART: SM00032 SMART: SM00020 SMART: SM00327 PROSITE: PS50923 PROSITE: PS50240 PROSITE: PS00134 PROSITE: PS00135 PROSITE: PS50234 SUPERFAMILY: SSF50494 PIRSF: PIRSF001154

IPI00303963 - C2, COMPLEMENT C2 PRECURSOR (FRAGMENT).

Uniprot Accession: Q95IG1

Uniprot ID: Q95IG1_HUMAN

Mapping: Chr 6, 32030300 - 32048254

Entrez Gene: 717

Entrez MapView: Geneprod

+All IPI Database Cross References

UniProtKB/Swiss-Prot: P06681
UniProtKB/Swiss-Prot: CO2_HUMAN
Vega: OTTHUMP00000014614
Vega: OTTHUMP00000029277
Vega: OTTHUMP00000029712
REFSEQ_REVIEWED: NP_000054
REFSEQ_REVIEWED: GI:14550407
UniProtKB/TrEMBL: Q53GZ8
UniProtKB/TrEMBL: Q53GZ8_HUMAN
UniProtKB/TrEMBL: Q53HP3
UniProtKB/TrEMBL: Q53HP3_HUMAN
UniProtKB/TrEMBL: Q5JP69
UniProtKB/TrEMBL: Q5JP69_HUMAN
UniProtKB/TrEMBL: Q95IG1
UniProtKB/TrEMBL: Q95IG1_HUMAN
ENSEMBL: ENSP00000299367
ENSEMBL: ENSG00000166278
ENSEMBL: ENSP00000364660
ENSEMBL: ENSG00000204364
ENSEMBL: ENSP00000372853
ENSEMBL: ENSG00000206372
UniParc: UPI000000DA4D
HGNC: 1248
Entrez Gene: 717
UniGene: Hs.408903
CCDS: CCDS4728.1
trome: HTR008384
UTRdb: BB006791
UTRdb: BB234777
UTRdb: BB283129
UTRdb: BB323790
UTRdb: BB323791
UTRdb: BB323793
UTRdb: BB379919
UTRdb: BB379921
UTRdb: BB381780
UTRdb: BB381785
UTRdb: BB381786
UTRdb: BB381790
UTRdb: CC265704
UTRdb: CC316773
UTRdb: CC360500
UTRdb: CC360503
UTRdb: CC425032
UTRdb: CC427132
UTRdb: CC427140
RZPD: Hs.408903
CleanEx: HS_C2
InterPro: IPR011360
InterPro: IPR009003
InterPro: IPR001254
InterPro: IPR001314
InterPro: IPR000436
InterPro: IPR002035
Pfam: PF00084
Pfam: PF00089
Pfam: PF00092
PRINTS: PR00722
PRINTS: PR00453
SMART: SM00032
SMART: SM00020
SMART: SM00327
PROSITE: PS50923
PROSITE: PS50240
PROSITE: PS00134
PROSITE: PS00135
PROSITE: PS50234
SUPERFAMILY: SSF50494
PIRSF: PIRSF001154

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14226)
Rat: C2, COMPLEMENT COMPONENT 2.
Mouse: C2, ISOFORM LONG OF COMPLEMENT C2 PRECURSOR (FRAGMENT).
Mouse: C2, ISOFORM SHORT OF COMPLEMENT C2 PRECURSOR (FRAGMENT).
Human: C2, COMPLEMENT C2 PRECURSOR (FRAGMENT).
Human: C2, COMPLEMENT COMPONENT 2.
Human: C2, C2 PROTEIN.
Human: C2, COMPLEMENT COMPONENT 2 (FRAGMENT).
Human: C2, COMPLEMENT COMPONENT 2.
Human: C2, COMPLEMENT COMPONENT 2.
Human: C2, COMPLEMENT COMPONENT 2.
Human: C2, COMPLEMENT COMPONENT 2.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14226)

Rat: C2, COMPLEMENT COMPONENT 2.

Mouse: C2, ISOFORM LONG OF COMPLEMENT C2 PRECURSOR (FRAGMENT).

Mouse: C2, ISOFORM SHORT OF COMPLEMENT C2 PRECURSOR (FRAGMENT).

Human: C2, COMPLEMENT C2 PRECURSOR (FRAGMENT).

Human: C2, COMPLEMENT COMPONENT 2.

Human: C2, C2 PROTEIN.

Human: C2, COMPLEMENT COMPONENT 2 (FRAGMENT).

Human: C2, COMPLEMENT COMPONENT 2.

Annotations for C2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular space	C	TAS	RCA	ISS
cellular_component	C			ND
extracellular region	C	IEA	IEA
protein binding	F			IDA
peptidase activity	F	IEA	IEA	IEA
hydrolase activity	F		IEA
classical-complement-pathway C3/C5 convertase activity	F	IEA	IEA
serine-type endopeptidase activity	F	IEA	IEA IEA	IEA
catalytic activity	F	IEA
response to nutrient	P			IEP
complement activation	P		IEA IEA
innate immune response	P	IEA	IEA
complement activation, classical pathway	P	TAS	IEA	ISS
immune response	P		IEA
proteolysis	P	IEA	IEA	IEA

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Macular Degeneration	D			ISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Complement and coagulation cascades (04610)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway