IpiRecord: IPI00304986

IPI00304986 - IRAK2, INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE-LIKE 2.
Uniprot Accession: O43187
Uniprot ID: IRAK2_HUMAN
Mapping: Chr 3, 10181563 - 10260427
Entrez Gene: 3656
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4912)
Rat: Irak2, 64 KDA PROTEIN.
Mouse: Irak2, ISOFORM 2 OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE-LIKE 2.
Mouse: Irak2, ISOFORM 1 OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE-LIKE 2.
Mouse: Irak2, 18 KDA PROTEIN.
Mouse: Irak2, ISOFORM 3 OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE-LIKE 2.
Mouse: Irak2, ISOFORM 4 OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE-LIKE 2.
Mouse: Irak2, 11 KDA PROTEIN.
Rat: Irak2, 61 KDA PROTEIN.
Rat: Irak2, INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE-LIKE 2.
Rat: Irak2, 80 KDA PROTEIN.
Human: IRAK2, INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE-LIKE 2.

Annotations for IRAK2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cellular_componentCND 
cell surfaceCIEP ISS 
NF-kappaB-inducing kinase activityFTAS ISS 
protein bindingFIEA IEA 
identical protein bindingFIPI ISS 
protein kinase activityFIEA ISS IEA 
ATP bindingFIEA IEA IEA 
protein serine/threonine kinase activityFIEA ISS 
protein-tyrosine kinase activityFISS 
activation of NF-kappaB-inducing kinasePIDA 
inflammatory responsePTAS ISS 
protein amino acid autophosphorylationPIDA 
regulation of apoptosisPRCA ISS 
lipopolysaccharide-mediated signaling pathwayPIEA IDA ISS 
I-kappaB kinase/NF-kappaB cascadePTAS ISS 
apoptosisPRCA ISS 
protein amino acid phosphorylationPTAS IEA ISS IEA 
signal transductionPIEA IEA IEA 
negative regulation of transcription factor activityPIEA IDA ISS 
activation of NF-kappaB transcription factorPIEA IDA ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway