| IPI00305356 - CYP7A1, CYTOCHROME P450 7A1. | |
|---|---|
| Uniprot Accession: P22680 | |
| Uniprot ID: CP7A1_HUMAN | |
| Mapping: Chr 8, 59565292 - 59575275 | |
| Entrez Gene: 1581 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5203) |
|---|
| Rat: Cyp7a1, CYTOCHROME P450 7A1. |
| Mouse: Cyp7a1, CYTOCHROME P450 7A1. |
| Mouse: Cyp7a1, CLONE:C730003A10 PRODUCT:CYTOCHROME P450, 7A1, FULL INSERT SEQUENCE. |
| Human: CYP7A1, CYTOCHROME P450 7A1. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| microsome | C | IEA | IDA | IEA TAS ISS IDA |
| integral to membrane | C | RCA | ISS | |
| endoplasmic reticulum | C | IEA | IEA | IEA |
| membrane | C | IEA | IEA | IEA |
| metal ion binding | F | IEA | IEA | IEA |
| cholesterol 7-alpha-monooxygenase activity | F | IEA | IDA IDA IDA | IEA IDA ISS |
| iron ion binding | F | IEA | IEA IEA | IEA |
| monooxygenase activity | F | IEA | IEA IEA | IEA |
| heme binding | F | IEA | IEA | IEA |
| oxidoreductase activity | F | IEA | ||
| lipid metabolic process | P | IEA | IEA | IEA |
| cholesterol metabolic process | P | IEA | ||
| bile acid biosynthetic process | P | NR | TAS ISS | |
| cholesterol catabolic process | P | IEA | IDA IDA | IEA ISS |
| steroid metabolic process | P | IEA | IEA | IEA |
| electron transport | P | IEA | IEA | IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| behavior/neurological phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| lethality-postnatal | MP | Un | ||
| vision/eye phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| growth/size phenotype | MP | Un | ||
| liver/biliary system phenotype | MP | Un |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| bile acid biosynthetic pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| PPAR signaling pathway (03320) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Bile acid biosynthesis (00120) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |