IpiRecord: IPI00305356

IPI00305356 - CYP7A1, CYTOCHROME P450 7A1.
Uniprot Accession: P22680
Uniprot ID: CP7A1_HUMAN
Mapping: Chr 8, 59565292 - 59575275
Entrez Gene: 1581
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5203)
Rat: Cyp7a1, CYTOCHROME P450 7A1.
Mouse: Cyp7a1, CYTOCHROME P450 7A1.
Mouse: Cyp7a1, CLONE:C730003A10 PRODUCT:CYTOCHROME P450, 7A1, FULL INSERT SEQUENCE.
Human: CYP7A1, CYTOCHROME P450 7A1.

Annotations for CYP7A1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
microsomeCIEA IDA IEA TAS ISS IDA 
integral to membraneCRCA ISS 
endoplasmic reticulumCIEA IEA IEA 
membraneCIEA IEA IEA 
metal ion bindingFIEA IEA IEA 
cholesterol 7-alpha-monooxygenase activityFIEA IDA IDA IDA IEA IDA ISS 
iron ion bindingFIEA IEA IEA IEA 
monooxygenase activityFIEA IEA IEA IEA 
heme bindingFIEA IEA IEA 
oxidoreductase activityFIEA 
lipid metabolic processPIEA IEA IEA 
cholesterol metabolic processPIEA 
bile acid biosynthetic processPNR TAS ISS 
cholesterol catabolic processPIEA IDA IDA IEA ISS 
steroid metabolic processPIEA IEA IEA 
electron transportPIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
behavior/neurological phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
lethality-embryonic/perinatalMPUn
lethality-postnatalMPUn
vision/eye phenotypeMPUn
digestive/alimentary phenotypeMPUn
growth/size phenotypeMPUn
liver/biliary system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
bile acid biosynthetic pathwayWIEA

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
PPAR signaling pathway (03320)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Bile acid biosynthesis (00120)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway