IpiRecord: IPI00307162

IPI00307162 - VCL, ISOFORM 2 OF VINCULIN.
Uniprot Accession: Q5JQ13
Uniprot ID: Q5JQ13_HUMAN
Mapping: Chr 10, 75427878 - 75549924
Entrez Gene: 7414
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12185)
Rat: Vcl_predicted, SIMILAR TO VINCULIN.
Mouse: Vcl, VINCULIN.
Mouse: Vcl, VINCULIN.
Human: VCL, ISOFORM 1 OF VINCULIN.
Human: VCL, ISOFORM 2 OF VINCULIN.
Human: VCL, ISOFORM 3 OF VINCULIN.

Annotations for VCL and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
actin cytoskeletonCIEA 
stress fiberCIDA 
cell-matrix junctionCISS 
plasma membraneCIDA 
fascia adherensCIDA 
actin filamentCIDA 
intercellular junctionCIDA ISS 
focal adhesionCIDA ISS IDA 
costamereCIDA ISS ISS 
protein complexCISS 
cytoskeletonCIEA 
cytoplasmCIEA 
adherens junctionCIDA ISS 
cell junctionCIEA 
oxidoreductase activityFRCA ISS 
actin bindingFIEA 
protein bindingFIPI ISS 
alpha-catenin bindingFISS 
structural molecule activityFIEA IEA 
Rho GTPase bindingFIPI 
cell adhesionPIDA ISS ISS 
apical junction assemblyPISS 
regulation of cell migrationPIDA ISS 
metabolic processPRCA ISS 
negative regulation of cell migrationPISS 
lamellipodium biogenesisPIDA ISS 
cell motilityPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (11)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn
craniofacial phenotypeMPUn
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
muscle phenotypeMPUn
nervous system phenotypeMPUn
cardiovascular system phenotypeMPUn
digestive/alimentary phenotypeMPUn
limbs/digits/tail phenotypeMPUn
growth/size phenotypeMPUn
life span-post-weaning/agingMPUn

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Cardiomyopathy, HypertrophicDISS
Cardiomyopathy, CongestiveDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway