| IPI00328867 - SRC, ISOFORM 2 OF PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC. | |
|---|---|
| Uniprot Accession: Q76P87 | |
| Uniprot ID: Q76P87_HUMAN | |
| Mapping: Chr 20, 35406502 - 35467239 | |
| Entrez Gene: 6714 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4144) |
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| Rat: Src, NEURONAL C-SRC TYROSINE-SPECIFIC PROTEIN KINASE. |
| Mouse: Src, NEURONAL PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC. |
| Mouse: Src, ROUS SARCOMA ONCOGENE ISOFORM 2. |
| Mouse: Src, ROUS SARCOMA ONCOGENE ISOFORM 1. |
| Human: SRC, ISOFORM 2 OF PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC. |
| Human: SRC, ISOFORM 1 OF PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC. |
| Human: SRC, NORVEGICUS TYROSINE PROTEIN KINASE PP60-C-SRC MRNA. |
| Human: SRC, 60 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| plasma membrane | C | IDA | ||
| intracellular | C | IEA | ||
| protein-tyrosine kinase activity | F | IEA | IMP | IDA ISS IEA |
| ATP binding | F | IEA | IEA IEA | IEA |
| protein serine/threonine kinase activity | F | ISS | ||
| kinase activity | F | IMP | TAS ISS | |
| protein C-terminus binding | F | IPI | ||
| protein kinase activity | F | IDA | ISS | |
| protein binding | F | IPI IPI | ISS IDA IDA | |
| transferase activity | F | IEA | IEA | |
| nucleotide binding | F | IEA | IEA | |
| intracellular signaling cascade | P | IEA | IEA | IEA |
| regulation of progression through cell cycle | P | IEA | ||
| positive regulation of insulin receptor signaling pathway | P | IDA | ||
| peptidyl-tyrosine phosphorylation | P | IDA | ISS | |
| transcytosis | P | IDA | ||
| cell proliferation | P | IDA | ||
| protein amino acid phosphorylation | P | IEA | IDA | ISS IEA |
| response to acid | P | IEP | ||
| forebrain development | P | IGI | ISS | |
| cell-cell adhesion | P | IEP | ||
| epidermal growth factor receptor signaling pathway | P | IEP | ||
| response to stress | P | IDA | ||
| platelet-derived growth factor receptor signaling pathway | P | IEP | ||
| nerve growth factor receptor signaling pathway | P | IDA | ||
| response to mineralocorticoid stimulus | P | IDA | ||
| positive regulation of apoptosis | P | IDA | ||
| positive regulation of cell adhesion | P | IDA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| craniofacial phenotype | MP | Un | ||
| behavior/neurological phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| skeleton phenotype | MP | Un | ||
| lethality-postnatal | MP | Un | ||
| respiratory system phenotype | MP | Un | ||
| limbs/digits/tail phenotype | MP | Un | ||
| hematopoietic system phenotype | MP | Un | ||
| reproductive system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Diabetes Mellitus, Non-Insulin-Dependent | D | ISS | ||
| Status Epilepticus | D | IED | ||
| Brain Ischemia | D | IED | ||
| Colonic Neoplasms | D | ISS | ||
| Neoplasm Metastasis | D | ISS | ||
| Hypertension | D | IED | ||
| Parkinsonian Disorders | D | IED |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| nerve growth factor signaling pathway | W | IDA | ||
| somatostatin signaling pathway | W | IDA | ||
| dopamine signaling pathway | W | IDA | ||
| platelet-derived growth factor signaling pathway | W | IEP | ||
| epidermal growth factor/neuregulin signaling pathway | W | IEP | ||
| ubiquitin/proteasome degradation pathway | W | IDA | ||
| pathway pertinent to signaling in the brain | W | IDA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| GnRH signaling pathway (04912) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Epithelial cell signaling in Helicobacter pylori infection (05120) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Adherens junction (04520) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| VEGF signaling pathway (04370) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Tight junction (04530) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Gap junction (04540) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |