IpiRecord: IPI00329185

IPI00329185 - PLCG2, 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2.
Uniprot Accession: P16885
Uniprot ID: PLCG2_HUMAN
Mapping: Chr 16, 80370408 - 80549399
Entrez Gene: 5336
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14109)
Rat: Plcg2, 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2.
Mouse: Plcg2, SEQUENCE.
Rat: Plcg2, 121 KDA PROTEIN.
Rat: Plcg2, 120 KDA PROTEIN.
Human: PLCG2, 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2.
Human: PLCG2, UNCHARACTERIZED PROTEIN PLCG2.
Human: PLCG2, PROTEIN.

Annotations for PLCG2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
signal transducer activityFIEA IEA 
protein bindingFIPI ISS 
hydrolase activityFIEA IEA 
phosphoinositide phospholipase C activityFIEA IEA 
calcium ion bindingFIEA IEA 
phospholipase C activityFTAS ISS 
intracellular signaling cascadePIEA IEA 
phospholipid metabolic processPNR ISS 
cell surface receptor linked signal transductionPNR ISS 
lipid metabolic processPIEA 
lipid catabolic processPIEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
immune system phenotypeMPUn
skeleton phenotypeMPUn
hematopoietic system phenotypeMPUn
renal/urinary system phenotypeMPUn
absent pre-B cellsNISS

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
Wnt signaling pathwayWIEA
inositol phosphate metabolic pathwayWIEA
phosphatidylinositol 3 kinase-Akt signaling pathwayWIEA

KEGG Pathway (11)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Epithelial cell signaling in Helicobacter pylori infection (05120)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Cholera - Infection (05110)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Calcium signaling pathway (04020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Inositol phosphate metabolism (00562)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Phosphatidylinositol signaling system (04070)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway