| IPI00332355 - BCR, BREAKPOINT CLUSTER REGION PROTEIN. | |
|---|---|
| Uniprot Accession: Q12844 | |
| Uniprot ID: Q12844_HUMAN | |
| Mapping: Chr 22, 21852552 - 21990224 | |
| Entrez Gene: 613 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14220) |
|---|
| Rat: Bcr_predicted, SIMILAR TO BREAKPOINT CLUSTER REGION ISOFORM 1. |
| Mouse: Bcr, BREAKPOINT CLUSTER REGION PROTEIN. |
| Rat: Bcr_predicted, SIMILAR TO BREAKPOINT CLUSTER REGION ISOFORM 1. |
| Human: BCR, ISOFORM 1 OF BREAKPOINT CLUSTER REGION PROTEIN. |
| Human: BCR, BREAKPOINT CLUSTER REGION PROTEIN. |
| Human: BCR, CLUSTER REGION PROTEIN. |
| Human: BCR, BREAKPOINT CLUSTER REGION PROTEIN (FRAGMENT). |
| Human: BCR, BREAKPOINT CLUSTER REGION PROTEIN (FRAGMENT). |
| Human: BCR, BCR. |
| Human: BCR, ISOFORM 2 OF BREAKPOINT CLUSTER REGION PROTEIN. |
| Human: BCR, BREAKPOINT CLUSTER REGION PROTEIN. |
| Human: BCR, 17 KDA PROTEIN. |
| Human: BCR, BCRE18/ABL1E3 FUSION PROTEIN (FRAGMENT). |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular_component | C | ND | ||
| cytoplasm | C | IDA | ||
| intracellular | C | IEA | IEA | IEA |
| guanyl-nucleotide exchange factor activity | F | IEA | IEA IEA | IEA |
| kinase activity | F | IEA | ||
| protein binding | F | IDA | ||
| protein serine/threonine kinase activity | F | NAS | IEA | ISS |
| GTPase activator activity | F | NAS | TAS | ISS |
| transferase activity | F | IEA | ||
| Rho guanyl-nucleotide exchange factor activity | F | IEA | IEA | IEA |
| signal transduction | P | IEA | IEA | |
| intracellular signaling cascade | P | NAS IEA | IEA | IEA |
| regulation of progression through cell cycle | P | IDA | ||
| protein amino acid phosphorylation | P | ISS | ||
| platelet-derived growth factor receptor signaling pathway | P | IDA | ||
| regulation of Rho protein signal transduction | P | IEA | IEA | IEA |
| brain development | P | IGI |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| behavior/neurological phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| nervous system phenotype | MP | Un | ||
| hearing/vestibular/ear phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Coronary Restenosis | D | IEP | ||
| Leukemia, Myeloid, Chronic | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Chronic myeloid leukemia (05220) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |