IpiRecord: IPI00332355

IPI00332355 - BCR, BREAKPOINT CLUSTER REGION PROTEIN.
Uniprot Accession: Q12844
Uniprot ID: Q12844_HUMAN
Mapping: Chr 22, 21852552 - 21990224
Entrez Gene: 613
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14220)
Rat: Bcr_predicted, SIMILAR TO BREAKPOINT CLUSTER REGION ISOFORM 1.
Mouse: Bcr, BREAKPOINT CLUSTER REGION PROTEIN.
Rat: Bcr_predicted, SIMILAR TO BREAKPOINT CLUSTER REGION ISOFORM 1.
Human: BCR, ISOFORM 1 OF BREAKPOINT CLUSTER REGION PROTEIN.
Human: BCR, BREAKPOINT CLUSTER REGION PROTEIN.
Human: BCR, CLUSTER REGION PROTEIN.
Human: BCR, BREAKPOINT CLUSTER REGION PROTEIN (FRAGMENT).
Human: BCR, BREAKPOINT CLUSTER REGION PROTEIN (FRAGMENT).
Human: BCR, BCR.
Human: BCR, ISOFORM 2 OF BREAKPOINT CLUSTER REGION PROTEIN.
Human: BCR, BREAKPOINT CLUSTER REGION PROTEIN.
Human: BCR, 17 KDA PROTEIN.
Human: BCR, BCRE18/ABL1E3 FUSION PROTEIN (FRAGMENT).

Annotations for BCR and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cellular_componentCND 
cytoplasmCIDA 
intracellularCIEA IEA IEA 
guanyl-nucleotide exchange factor activityFIEA IEA IEA IEA 
kinase activityFIEA 
protein bindingFIDA 
protein serine/threonine kinase activityFNAS IEA ISS 
GTPase activator activityFNAS TAS ISS 
transferase activityFIEA 
Rho guanyl-nucleotide exchange factor activityFIEA IEA IEA 
signal transductionPIEA IEA 
intracellular signaling cascadePNAS IEA IEA IEA 
regulation of progression through cell cyclePIDA 
protein amino acid phosphorylationPISS 
platelet-derived growth factor receptor signaling pathwayPIDA 
regulation of Rho protein signal transductionPIEA IEA IEA 
brain developmentPIGI 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
behavior/neurological phenotypeMPUn
lethality-embryonic/perinatalMPUn
nervous system phenotypeMPUn
hearing/vestibular/ear phenotypeMPUn

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Coronary RestenosisDIEP
Leukemia, Myeloid, ChronicDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway