IpiRecord: IPI00336003

IPI00336003 - BDNF, BRAIN-DERIVED NEUROTROPHIC FACTOR ISOFORM B PREPROPROTEIN.
Uniprot Accession: Q6YNR3
Uniprot ID: Q6YNR3_HUMAN
Mapping: Chr 11, 27633022 - 27699872
Entrez Gene: 627
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3626)
Rat: Bdnf, BRAIN-DERIVED NEUROTROPHIC FACTOR PRECURSOR.
Mouse: Bdnf, BRAIN-DERIVED NEUROTROPHIC FACTOR PRECURSOR.
Mouse: Bdnf, BRAIN DERIVED NEUROTROPHIC FACTOR ISOFORM 1.
Human: BDNF, BRAIN-DERIVED NEUROTROPHIC FACTOR PRECURSOR.
Human: BDNF, BRAIN-DERIVED NEUROTROPHIC FACTOR ISOFORM B PREPROPROTEIN.
Human: BDNF, BRAIN DERIVED NEUROTROPHIC FACTOR VARIANT.

Annotations for BDNF and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCRCA ISS 
cytoplasmic membrane-bound vesicleCIEA IDA IDA ISS 
synaptic vesicleCIDA 
growth factor activityFTAS IEA IEA IEA TAS ISS IEA 
protein bindingFIPI IPI ISS 
neurotrophin TRKB receptor bindingFIDA 
regulation of metabolic processPIEA IMP ISS 
ureteric bud developmentPIEA IDA ISS 
negative regulation of neuron apoptosisPIEA IMP 
neuron recognitionPIEA IMP ISS 
regulation of synaptic plasticityPIEA IDA 
glutamate secretionPIEA IPI 
regulation of long-term neuronal synaptic plasticityPIDA 
dendrite developmentPIEA IMP ISS 
nerve developmentPIEA IMP 
nervous system developmentPIDA ISS 
regulation of neuron apoptosisPIDA ISS 
neuron differentiationPTAS 
axon guidancePIEA IMP ISS 
mitochondrial electron transport, NADH to ubiquinonePIMP 
inner ear developmentPIEA IMP 
positive regulation of neuron differentiationPIEA IDA ISS 
regulation of retinal programmed cell deathPIEA IDA ISS 
negative regulation of neuroblast proliferationPIEA IDA ISS 
feeding behaviorPIEA IMP ISS 
axon target recognitionPIEA IMP ISS 
negative regulation of striated muscle developmentPIMP 
anti-apoptosisPIEA IDA ISS 
regulation of short-term neuronal synaptic plasticityPIDA 
regulation of excitatory postsynaptic membrane potentialPIMP 
mechanoreceptor differentiationPIEA IGI ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (18)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
craniofacial phenotypeMPUn
homeostasis/metabolism phenotypeMPUn Un
behavior/neurological phenotypeMPUn Un Un Un Un Un Un Un Un Un
lethality-embryonic/perinatalMPUn
lethality-postnatalMPUn Un Un Un Un
taste/olfaction phenotypeMPUn Un
life span-post-weaning/agingMPUn Un Un
nervous system phenotypeMPUn Un Un Un Un Un Un Un Un Un Un
growth/size phenotypeMPUn Un Un Un Un Un Un Un Un Un
vision/eye phenotypeMPUn Un
normal phenotypeMPUn Un Un Un
digestive/alimentary phenotypeMPUn Un Un
reproductive system phenotypeMPUn Un Un Un
hearing/vestibular/ear phenotypeMPUn Un Un Un
respiratory system phenotypeMPUn
increased alcohol consumptionNIAGP
increased anxiety-related responseNIAGP

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
mitogen activated protein kinase signaling pathwayWIEA
Huntington disease pathwayWIEA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Huntington's disease (05040)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway