| IPI00336003 - BDNF, BRAIN-DERIVED NEUROTROPHIC FACTOR ISOFORM B PREPROPROTEIN. | |
|---|---|
| Uniprot Accession: Q6YNR3 | |
| Uniprot ID: Q6YNR3_HUMAN | |
| Mapping: Chr 11, 27633022 - 27699872 | |
| Entrez Gene: 627 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3626) |
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| Rat: Bdnf, BRAIN-DERIVED NEUROTROPHIC FACTOR PRECURSOR. |
| Mouse: Bdnf, BRAIN-DERIVED NEUROTROPHIC FACTOR PRECURSOR. |
| Mouse: Bdnf, BRAIN DERIVED NEUROTROPHIC FACTOR ISOFORM 1. |
| Human: BDNF, BRAIN-DERIVED NEUROTROPHIC FACTOR PRECURSOR. |
| Human: BDNF, BRAIN-DERIVED NEUROTROPHIC FACTOR ISOFORM B PREPROPROTEIN. |
| Human: BDNF, BRAIN DERIVED NEUROTROPHIC FACTOR VARIANT. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| extracellular space | C | RCA | ISS | |
| cytoplasmic membrane-bound vesicle | C | IEA | IDA IDA | ISS |
| synaptic vesicle | C | IDA | ||
| growth factor activity | F | TAS IEA | IEA IEA | TAS ISS IEA |
| protein binding | F | IPI | IPI | ISS |
| neurotrophin TRKB receptor binding | F | IDA | ||
| regulation of metabolic process | P | IEA | IMP | ISS |
| ureteric bud development | P | IEA | IDA | ISS |
| negative regulation of neuron apoptosis | P | IEA | IMP | |
| neuron recognition | P | IEA | IMP | ISS |
| regulation of synaptic plasticity | P | IEA | IDA | |
| glutamate secretion | P | IEA | IPI | |
| regulation of long-term neuronal synaptic plasticity | P | IDA | ||
| dendrite development | P | IEA | IMP | ISS |
| nerve development | P | IEA | IMP | |
| nervous system development | P | IDA ISS | ||
| regulation of neuron apoptosis | P | IDA | ISS | |
| neuron differentiation | P | TAS | ||
| axon guidance | P | IEA | IMP | ISS |
| mitochondrial electron transport, NADH to ubiquinone | P | IMP | ||
| inner ear development | P | IEA | IMP | |
| positive regulation of neuron differentiation | P | IEA | IDA | ISS |
| regulation of retinal programmed cell death | P | IEA | IDA | ISS |
| negative regulation of neuroblast proliferation | P | IEA | IDA | ISS |
| feeding behavior | P | IEA | IMP | ISS |
| axon target recognition | P | IEA | IMP | ISS |
| negative regulation of striated muscle development | P | IMP | ||
| anti-apoptosis | P | IEA | IDA | ISS |
| regulation of short-term neuronal synaptic plasticity | P | IDA | ||
| regulation of excitatory postsynaptic membrane potential | P | IMP | ||
| mechanoreceptor differentiation | P | IEA | IGI | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| craniofacial phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un | ||
| behavior/neurological phenotype | MP | Un Un Un Un Un Un Un Un Un Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| lethality-postnatal | MP | Un Un Un Un Un | ||
| taste/olfaction phenotype | MP | Un Un | ||
| life span-post-weaning/aging | MP | Un Un Un | ||
| nervous system phenotype | MP | Un Un Un Un Un Un Un Un Un Un Un | ||
| growth/size phenotype | MP | Un Un Un Un Un Un Un Un Un Un | ||
| vision/eye phenotype | MP | Un Un | ||
| normal phenotype | MP | Un Un Un Un | ||
| digestive/alimentary phenotype | MP | Un Un Un | ||
| reproductive system phenotype | MP | Un Un Un Un | ||
| hearing/vestibular/ear phenotype | MP | Un Un Un Un | ||
| respiratory system phenotype | MP | Un | ||
| increased alcohol consumption | N | IAGP | ||
| increased anxiety-related response | N | IAGP |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| mitogen activated protein kinase signaling pathway | W | IEA | ||
| Huntington disease pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Huntington's disease (05040) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |