IpiRecord: IPI00336178

IPI00336178 - PDGFRA, PRECURSOR.
Uniprot Accession: P16234-2
Uniprot ID: PGFRA_HUMAN
Mapping: Chr 4, 54790204 - 54859171
Entrez Gene: 5156
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12137)
Rat: Pdgfra, ALPHA-TYPE PLATELET-DERIVED GROWTH FACTOR RECEPTOR PRECURSOR.
Mouse: Pdgfra, ALPHA-TYPE PLATELET-DERIVED GROWTH FACTOR RECEPTOR PRECURSOR.
Mouse: Pdgfra, PLATELET DERIVED GROWTH FACTOR RECEPTOR, ALPHA POLYPEPTIDE.
Rat: Pdgfra, 55 KDA PROTEIN.
Rat: Pdgfra, (PDGF-R-ALPHA) ISOFORM 1.
Human: PDGFRA, PRECURSOR.
Human: PDGFRA, PRECURSOR.

Annotations for PDGFRA and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCISS 
integral to membraneCIEA IEA 
membraneCIEA IEA IEA 
platelet-derived growth factor alpha-receptor activityFIDA TAS ISS 
protein-tyrosine kinase activityFIEA IEA 
ATP bindingFIEA IEA IEA 
protein serine/threonine kinase activityFISS 
receptor activityFIEA IEA 
kinase activityFIEA 
platelet-derived growth factor bindingFIDA ISS 
transmembrane receptor protein tyrosine kinase activityFIEA 
nucleotide bindingFIEA IEA 
protein dimerization activityFNAS 
protein kinase activityFIEA 
vascular endothelial growth factor receptor activityFIEA IEA 
transferase activityFIEA IEA 
gliogenesisPIEP NAS 
cell proliferationPISS 
protein amino acid phosphorylationPIEA IEA 
lung developmentPIMP ISS 
extracellular matrix organization and biogenesisPIMP ISS 
transmembrane receptor protein tyrosine kinase signaling pathwayPIEA IEA 
male genitalia developmentPIMP ISS 
anatomical structure morphogenesisPIMP ISS 
cell surface receptor linked signal transductionPISS 
odontogenesis (sensu Vertebrata)PIMP ISS 
organ morphogenesisPIMP ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (22)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
cellular phenotypeMPUn
craniofacial phenotypeMPUn Un Un Un
behavior/neurological phenotypeMPUn
homeostasis/metabolism phenotypeMPUn Un Un
immune system phenotypeMPUn
embryogenesis phenotypeMPUn Un Un
lethality-embryonic/perinatalMPUn Un Un Un
lethality-postnatalMPUn Un
muscle phenotypeMPUn
skeleton phenotypeMPUn Un Un Un
nervous system phenotypeMPUn Un Un Un
respiratory system phenotypeMPUn Un
limbs/digits/tail phenotypeMPUn
normal phenotypeMPUn
cardiovascular system phenotypeMPUn Un Un
digestive/alimentary phenotypeMPUn Un Un Un
hematopoietic system phenotypeMPUn Un
life span-post-weaning/agingMPUn
no phenotypic analysisMPUn
growth/size phenotypeMPUn Un
pigmentation phenotypeMPUn

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
EosinophiliaDISS
Hypereosinophilic SyndromeDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Calcium signaling pathway (04020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayNot present in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway