IpiRecord: IPI00375340

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
external side of plasma membrane	C		IDA IDA	ISS IEA
caveola	C			IEP
membrane	C	IEA	IEA IEA	IEA
integral to membrane	C		RCA	ISS IEA
tumor necrosis factor receptor activity	F			TAS
receptor activity	F		IEA IEA	TAS
protein binding	F	IEA	IPI	IPI IEA
transmembrane receptor activity	F	IEA	IEA	NAS IEA
menstrual cycle	P			IEP
transformed cell apoptosis	P		IDA	ISS IEA
positive regulation of apoptosis	P		IGI
response to peptide hormone stimulus	P			IEP
negative thymic T cell selection	P		IMP	ISS IEA
response to hypoxia	P			IEP
immune response	P	IEA	IEA	IEA
induction of apoptosis via death domain receptors	P		IMP IDA IGI IMP	ISS IEA
apoptosis	P	IEA	IGI ISS	TAS ISS IEA
response to estrogen stimulus	P			IEP
inflammatory cell apoptosis	P		IDA IMP	ISS IEA
activated T cell apoptosis	P		IDA	ISS IEA
induction of apoptosis	P			IEP
signal transduction	P	IEA	IEA	IEA
induction of apoptosis by extracellular signals	P			IMP
response to drug	P			IEP
aging	P			IEP

Cellular Component

Biological Process

Molecular Function

Phenotype (20)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un
skin/coat/nails phenotype	MP		Un
behavior/neurological phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
immune system phenotype	MP		Un Un Un Un Un Un
renal/urinary system phenotype	MP		Un Un
nervous system phenotype	MP		Un
respiratory system phenotype	MP		Un
tumorigenesis	MP		Un
cardiovascular system phenotype	MP		Un
digestive/alimentary phenotype	MP		Un
reproductive system phenotype	MP		Un
hearing/vestibular/ear phenotype	MP		Un
hematopoietic system phenotype	MP		Un Un Un Un Un
no phenotypic analysis	MP		Un
growth/size phenotype	MP		Un Un
liver/biliary system phenotype	MP		Un Un Un
pigmentation phenotype	MP		Un
life span-post-weaning/aging	MP		Un Un Un Un

Disease (12)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Lymphoproliferative Disorders	D			ISS
Brain Injuries	D			IEP
Ocular Hypertension	D			IEP
Retinal Detachment	D			IEP
Asthma	D			IEP
Nephrosis	D			IEP
Cardiomyopathy, Congestive	D			IEP
Brain Ischemia	D			IEP
Colonic Neoplasms	D			IEP
Brain Diseases, Metabolic	D			IEP
Reperfusion Injury	D			IEP
Varicocele	D			IEP

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
intrinsic apoptotic pathway	W			IEP
extrinsic death receptor pathway	W			IEP

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Apoptosis (04210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
MAPK signaling pathway (04010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Type I diabetes mellitus (04940)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cytokine-cytokine receptor interaction (04060)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway