| IPI00383682 - RB1, RB1 PROTEIN. | |
|---|---|
| Uniprot Accession: Q92728 | |
| Uniprot ID: Q92728_HUMAN | |
| Mapping: Chr 13, 47775912 - 47954123 | |
| Entrez Gene: 5925 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12532) |
|---|
| Rat: Rb1, SIMILAR TO RETINOBLASTOMA-ASSOCIATED PROTEIN. |
| Mouse: Rb1, RETINOBLASTOMA-ASSOCIATED PROTEIN. |
| Rat: Rb1, SIMILAR TO RETINOBLASTOMA-ASSOCIATED PROTEIN. |
| Human: RB1, RETINOBLASTOMA-ASSOCIATED PROTEIN. |
| Human: RB1, RB1 PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| chromatin | C | TAS | ISS | |
| transcription factor complex | C | IDA | ISS IEA | |
| spindle | C | IDA | ISS IEA | |
| PML body | C | IDA | ISS | |
| nucleus | C | TAS NAS | IDA IDA IDA IDA | IDA ISS ISS IEA |
| transcription factor activity | F | TAS | ISS | |
| kinase binding | F | IDA | ISS ISS | |
| androgen receptor binding | F | NAS | ISS | |
| protein binding | F | IPI IPI IPI IPI IPI IPI | IPI IPI IPI IPI IPI IPI | IPI ISS ISS |
| molecular_function | F | ND | ||
| transcription coactivator activity | F | NAS | ISS | |
| DNA binding | F | IEA | IEA | |
| transcription repressor activity | F | IDA | ISS IEA | |
| transcription factor binding | F | IPI | IEA | |
| regulation of progression through cell cycle | P | IMP | ISS | |
| cell cycle checkpoint | P | TAS | ISS | |
| negative regulation of transcription, DNA-dependent | P | IDA | ISS | |
| negative regulation of cell proliferation | P | IMP IGI | ISS IEA | |
| G1/S transition of mitotic cell cycle | P | IMP | ISS IEA | |
| androgen receptor signaling pathway | P | NAS | ISS | |
| negative regulation of progression through cell cycle | P | IEA | IMP | ISS |
| striated muscle cell differentiation | P | IGI | ISS IEA | |
| negative regulation of protein kinase activity | P | IPI | ISS ISS | |
| chromatin modification | P | IEA | IEA | IEA |
| M phase | P | NAS | ISS | |
| negative regulation of cell growth | P | TAS | ISS | |
| cell cycle arrest | P | IMP | ISS IEA | |
| enucleate erythrocyte differentiation | P | IGI | ||
| positive regulation of macrophage differentiation | P | IGI | ||
| transcription | P | IEA | IEA | IEA |
| regulation of lipid kinase activity | P | IDA | ISS ISS | |
| cell cycle | P | IEA | IEA | IEA |
| positive regulation of transcription, DNA-dependent | P | NAS | ISS | |
| G1 phase | P | TAS | ISS | |
| positive regulation of transcription from RNA polymerase II promoter | P | IDA IMP IGI | ISS IEA | |
| cell division | P | IMP | ISS IEA | |
| regulation of transcription, DNA-dependent | P | NAS | IEA | |
| negative regulation of transcription from RNA polymerase II promoter | P | TAS | IDA IGI | ISS ISS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| craniofacial phenotype | MP | Un | ||
| skin/coat/nails phenotype | MP | Un Un Un Un | ||
| cellular phenotype | MP | Un Un Un Un Un Un | ||
| behavior/neurological phenotype | MP | Un Un Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un Un | ||
| other phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un Un Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un Un Un Un Un Un | ||
| immune system phenotype | MP | Un Un Un Un | ||
| muscle phenotype | MP | Un Un Un | ||
| skeleton phenotype | MP | Un Un | ||
| lethality-postnatal | MP | Un Un | ||
| nervous system phenotype | MP | Un Un Un Un Un Un | ||
| respiratory system phenotype | MP | Un | ||
| vision/eye phenotype | MP | Un Un Un Un Un Un | ||
| tumorigenesis | MP | Un Un Un Un Un Un | ||
| normal phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un Un Un | ||
| reproductive system phenotype | MP | Un | ||
| hearing/vestibular/ear phenotype | MP | Un Un | ||
| hematopoietic system phenotype | MP | Un Un Un Un Un | ||
| life span-post-weaning/aging | MP | Un Un Un | ||
| no phenotypic analysis | MP | Un Un | ||
| growth/size phenotype | MP | Un Un Un Un | ||
| liver/biliary system phenotype | MP | Un Un Un Un | ||
| pigmentation phenotype | MP | Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glioma (05214) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Chronic myeloid leukemia (05220) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cell cycle (04110) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pancreatic cancer (05212) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |